Neuronal growth cones navigate over long distances along specific pathways to find their
correct targets. The mechanisms and molecules that direct this pathfinding are the topics of …

The functioning of the nervous system depends upon the underlying detailed and highly
stereotyped patterns of neuronal connectivity. How these precise patterns of synaptic …

IMMUNOGLOBULIN and T-cell receptor (TCR) molecules are central to the adaptive
immune system. Sequence conservation, similarities in domain structure, and usage of …

Small eye (Sey) mice homozygous for mutations in the Pax-6 gene have no lenses and no
nasal cavities. We have examined the ontogeny of eye and nasal defects in Sey/Sey …

The innervation of ventral longitudinal abdominal muscles (muscles 6, 7, 12, and 13) of third‐
instar Drosophila larvae was investigated with Nomarski, confocal, and electron microscopy …

An experimental analysis of neurogenesis requires a detailed understanding of wild-type
neural development. Recent DiI cell lineage studies have begun to elucidate the family of …

During nervous system development, neurons form reproducible synapses onto specific
targets. Here, we analyze the development of stereotyped synapses of the C. elegans HSNL …

We have used a retrograde labeling technique to identify motorneurons for each of the 30
body wall muscles of an abdominal hemisegment in the late stage 16 Drosophila embryo …

David Van Vactor, Helen Sink, Douglas Fambrough, Rosalie Tsoo, and Corey S. Goodman
Howard Hughes Medical Institute Department of Molecular and Cell Biology University of …

The neuromuscular system of Drosophila has been widely used in studies on synaptic
development. In the embryo, the cellular components of this model system are well …