Following the Birth, Life, and Death of mRNAs in Single Cells
BT Eichenberger, E Griesbach… - Annual Review of …, 2023 - annualreviews.org
Recent advances in single-molecule imaging of mRNAs in fixed and living cells have
enabled the lives of mRNAs to be studied with unprecedented spatial and temporal detail …
enabled the lives of mRNAs to be studied with unprecedented spatial and temporal detail …
Rhodamine‐Sensitized Two‐Photon Activation of a Red Light‐Absorbing BODIPY Photocage
R Weber, K Chok, S Junek, C Glaubitz… - … –A European Journal, 2023 - Wiley Online Library
Abstract Two‐photon (2P) activatable probes are of high value in biological and medical
chemistry since near infrared (NIR) light can penetrate deeply even in blood‐perfused tissue …
chemistry since near infrared (NIR) light can penetrate deeply even in blood‐perfused tissue …
A binary system based DNA tetrahedron and fluorogenic RNA aptamers for highly specific and label-free mRNA imaging in living cells
T Li, M Sun, S Xia, T Huang, RT Li, C Li, Z Dai, JX Chen… - Talanta, 2024 - Elsevier
Developing simple, rapid and specific mRNA imaging strategy plays an important role in the
early diagnosis of cancer and the new drugs development. Herein, we have established a …
early diagnosis of cancer and the new drugs development. Herein, we have established a …
A Blue Light and Two‐Photon Activatable Rhodamine Fluorophore
R Weber, S Junek, A Heckel - Chemistry–A European Journal, 2023 - Wiley Online Library
Photoactivatable fluorophores (PAFs) are powerful tools for biological imaging applications
because they provide spatiotemporal control of fluorescence distribution. Many of the …
because they provide spatiotemporal control of fluorescence distribution. Many of the …
Chromatic Selectivity of Coumarin‐Caged Oligonucleotides
J Kaufmann, F Sinsel, A Heckel - Chemistry–A European …, 2023 - Wiley Online Library
A system of two coumarin‐based caging groups is presented–one absorbing in the blue
(400–450 nm) and the other absorbing in the green (480–550 nm) part of the visible …
(400–450 nm) and the other absorbing in the green (480–550 nm) part of the visible …
Synthesis and characterization of 7-diethylamino-4-Chloromethyl coumarin: Spectroscopic analysis, molecular docking, and anticancer activity on large intestine …
Cancer, characterized by uncontrolled cell growth and metastasis, poses a significant global
health burden, ranking as a leading cause of mortality worldwide. Colorectal cancer (CRC) …
health burden, ranking as a leading cause of mortality worldwide. Colorectal cancer (CRC) …
Extending the Palette of Green Coumarin Photocages–Oligonucleotide Fragmentation and Superior 5'‐Caps
J Kaufmann, J Wolf, A Heckel - Chemistry–A European Journal, 2023 - Wiley Online Library
The possibilities of dicyanocoumarin (DCCM)‐modified oligonucleotides are expanded to
not just allow their release and therefore activation with green light (OFF→ ON) but to also …
not just allow their release and therefore activation with green light (OFF→ ON) but to also …
RNA Probes for visualization of sarcin/ricin loop depurination without background fluorescence
R Klimek, C Kaiser, NS Murmann… - Chemistry–An Asian …, 2022 - Wiley Online Library
Protein synthesis via ribosomes is a fundamental process in all known living organisms.
However, it can be completely stalled by removing a single nucleobase (depurination) at the …
However, it can be completely stalled by removing a single nucleobase (depurination) at the …