Synthesis methods of 1, 2, 3-/1, 2, 4-triazoles: A review

J Dai, S Tian, X Yang, Z Liu - Frontiers in Chemistry, 2022 - frontiersin.org
Triazole, comprising three nitrogen atoms and two carbon atoms, is divided into two isomers
1, 2, 3-triazole and 1, 2, 4-triazole. Compounds containing a triazole are one of the …

Recent advances in the chemistry of 1, 2, 4-triazoles: Synthesis, reactivity and biological activities

A Abdelli, S Azzouni, R Plais, A Gaucher, ML Efrit… - Tetrahedron …, 2021 - Elsevier
Triazoles are important heterocyclic motifs that are widely found in molecular architectures
with medicinal and pharmaceutical properties. Considering the importance of these …

An updated review on diverse range of biological activities of 1, 2, 4-triazole derivatives: Insight into structure activity relationship

O Gupta, T Pradhan, G Chawla - Journal of Molecular Structure, 2023 - Elsevier
Abstract Since its discovery 1, 2, 4-triazole ring has emerged as a prominent heterocyclic
scaffold in medicinal chemistry. It possesses a wide spectrum of biological activities such as …

Electrochemical synthesis of 1, 2, 4-triazole-fused heterocycles

Z Ye, M Ding, Y Wu, Y Li, W Hua, F Zhang - Green chemistry, 2018 - pubs.rsc.org
A reagent-free intramolecular dehydrogenative C–N cross-coupling reaction has been
developed under mild electrolytic conditions. In this atom-and step-economical one-pot …

[HTML][HTML] Triazolopyridine, a leitmotif of synthetic methods and pharmacological attributes: an extensive review

P Mohite, D Nahar, R Pawara, T Alqahtani… - Arabian Journal of …, 2023 - Elsevier
Background Famous synthetic pharmacophores like Filgotinib, Dapiprazole, and Trazodone
have Triazolopyridine as their primary building element. It has become more well-known in …

I2-Mediated Oxidative C–N and N–S Bond Formation in Water: A Metal-Free Synthesis of 4,5-Disubstituted/N-Fused 3-Amino-1,2,4-triazoles and 3-Substituted 5 …

N Jatangi, N Tumula, RK Palakodety… - The Journal of Organic …, 2018 - ACS Publications
An environmentally benign and convenient strategy for the synthesis of 4, 5-disubstituted/N-
fused 3-amino-1, 2, 4-triazoles and 3-substituted 5-amino-1, 2, 4-thiadiazoles from …

Tautomerism and structure of azoles: nuclear magnetic resonance spectroscopy

LI Larina - Advances in heterocyclic chemistry, 2018 - Elsevier
This review provides comprehensive data (from the author's work and the literature) on
tautomerism of pyrazoles, imidazoles, 1, 2, 3-and 1, 2, 4-triazoles, tetrazoles …

Exploring the chemistry and therapeutic potential of triazoles: a comprehensive literature review

A Jain, P Piplani - Mini Reviews in Medicinal Chemistry, 2019 - ingentaconnect.com
Triazole is a valuable platform in medicinal chemistry, possessing assorted pharmacological
properties, which could play a major role in the common mechanisms associated with …

A Review on Chemistry and Methods of Synthesis of 1, 2, 4‐Triazole Derivatives

S Couto Rodrigues… - The Chemical …, 2024 - Wiley Online Library
This review provides a comprehensive overview of research on 1, 2, 4‐triazoles conducted
over the last fifteen years. 1, 2, 4‐Triazoles are highly significant in the pharmaceutical …

I2-Catalyzed Oxidative N–S Bond Formation: Metal-Free Regiospecific Synthesis of N-Fused and 3,4-Disubstituted 5-Imino-1,2,4-thiadiazoles

N Tumula, N Jatangi, RK Palakodety… - The Journal of …, 2017 - ACS Publications
A novel and expeditious approach for the synthesis of N-fused and 3, 4-disubstituted 5-imino-
1, 2, 4-thiadiazole derivatives has been achieved through the molecular iodine-catalyzed …