Mechanisms of exercise as a preventative measure to muscle wasting
Skeletal muscle is the most abundant tissue in healthy individuals and it has important roles
in health beyond voluntary movement. The overall mass and energy requirements of …
in health beyond voluntary movement. The overall mass and energy requirements of …
Effects of aging and lifelong aerobic exercise on basal and exercise-induced inflammation
KM Lavin, RK Perkins, B Jemiolo… - Journal of Applied …, 2020 - journals.physiology.org
Age-associated chronic basal inflammation compromises muscle mass and adaptability, but
exercise training may exert an anti-inflammatory effect. This investigation assessed basal …
exercise training may exert an anti-inflammatory effect. This investigation assessed basal …
Controversies in TWEAK-Fn14 signaling in skeletal muscle atrophy and regeneration
Skeletal muscle is one of the largest functional tissues in the human body; it is highly plastic
and responds dramatically to anabolic and catabolic stimuli, including weight training and …
and responds dramatically to anabolic and catabolic stimuli, including weight training and …
The 24-hour molecular landscape after exercise in humans reveals MYC is sufficient for muscle growth
S Edman, RG Jones III, PR Jannig… - EMBO …, 2024 - embopress.org
A detailed understanding of molecular responses to a hypertrophic stimulus in skeletal
muscle leads to therapeutic advances aimed at promoting muscle mass. To decode the …
muscle leads to therapeutic advances aimed at promoting muscle mass. To decode the …
Skeletal muscle signature of a champion sprint runner
S Trappe, N Luden, K Minchev… - Journal of Applied …, 2015 - journals.physiology.org
We had the unique opportunity to study the skeletal muscle characteristics, at the single fiber
level, of a world champion sprint runner who is the current indoor world record holder in the …
level, of a world champion sprint runner who is the current indoor world record holder in the …
Human skeletal muscle macrophages increase following cycle training and are associated with adaptations that may facilitate growth
Skeletal muscle macrophages participate in repair and regeneration following injury.
However, their role in physiological adaptations to exercise is unexplored. We determined …
However, their role in physiological adaptations to exercise is unexplored. We determined …
[HTML][HTML] A novel voluntary weightlifting model in mice promotes muscle adaptation and insulin sensitivity with simultaneous enhancement of autophagy and mTOR …
Our understanding of the molecular mechanisms underlying adaptations to resistance
exercise remains elusive despite the significant biological and clinical relevance. We …
exercise remains elusive despite the significant biological and clinical relevance. We …
Transcriptome response of human skeletal muscle to divergent exercise stimuli
JM Dickinson, AC D'Lugos… - Journal of Applied …, 2018 - journals.physiology.org
Aerobic (AE) and resistance exercise (RE) elicit unique adaptations in skeletal muscle that
have distinct implications for health and performance. The purpose of this study was to …
have distinct implications for health and performance. The purpose of this study was to …
Resistance training regulates gene expression of molecules associated with intramyocellular lipids, glucose signaling and fiber size in old rats
Sarcopenia is a complex multifactorial process, some of which involves fat infiltration.
Intramyocellular lipid (IMCL) accumulation is postulated to play a role on sarcopenia during …
Intramyocellular lipid (IMCL) accumulation is postulated to play a role on sarcopenia during …
Muscle health and performance in monozygotic twins with 30 years of discordant exercise habits
Introduction Physical health and function depend upon both genetic inheritance and
environmental factors (eg, exercise training). Purpose To enhance the understanding of …
environmental factors (eg, exercise training). Purpose To enhance the understanding of …