[HTML][HTML] Exosome engineering in cell therapy and drug delivery

S Sadeghi, FR Tehrani, S Tahmasebi, A Shafiee… - …, 2023 - Springer
Cell-derived exosomes have opened new horizons in modern therapy for advanced drug
delivery and therapeutic applications, due to their key features such as low immunogenicity …

Current advances in the use of exosomes, liposomes, and bioengineered hybrid nanovesicles in cancer detection and therapy

A Mukherjee, B Bisht, S Dutta, MK Paul - Acta Pharmacologica Sinica, 2022 - nature.com
Three major approaches of cancer therapy can be enunciated as delivery of biotherapeutics,
tumor image analysis, and immunotherapy. Liposomes, artificial fat bubbles, are long known …

[HTML][HTML] Therapeutic strategy of mesenchymal-stem-cell-derived extracellular vesicles as regenerative medicine

Y Matsuzaka, R Yashiro - International Journal of Molecular Sciences, 2022 - mdpi.com
Extracellular vesicles (EVs) are lipid bilayer membrane particles that play critical roles in
intracellular communication through EV-encapsulated informative content, including …

Extracellular vesicles and their engineering strategies, delivery systems, and biomedical applications

C Yang, Y Xue, Y Duan, C Mao, M Wan - Journal of Controlled Release, 2024 - Elsevier
Extracellular vesicles are nanoscale vesicles that can be secreted by all cell types, are
intracellular in origin and have the same composition as their parent cells, play a key role in …

Exosome-bearing hydrogels and cardiac tissue regeneration

H Amini, AR Namjoo, MT Narmi, N Mardi… - Biomaterials …, 2023 - spj.science.org
Background In recent years, cardiovascular disease in particular myocardial infarction (MI)
has become the predominant cause of human disability and mortality in the clinical setting …

Exosomes in brain diseases: Pathogenesis and therapeutic targets

Q Si, L Wu, D Pang, P Jiang - MedComm, 2023 - Wiley Online Library
Exosomes are extracellular vesicles with diameters of about 100 nm that are naturally
secreted by cells into body fluids. They are derived from endosomes and are wrapped in …

[HTML][HTML] Drug resistance in cancers: A free pass for bullying

J Li, X Li, Q Guo - Cells, 2022 - mdpi.com
The cancer burden continues to grow globally, and drug resistance remains a substantial
challenge in cancer therapy. It is well established that cancerous cells with clonal dysplasia …

Understanding exosomes: Part 1—Characterization, quantification and isolation techniques

RJ Miron, Y Zhang - Periodontology 2000, 2024 - Wiley Online Library
Exosomes are the smallest subset of extracellular signaling vesicles secreted by most cells
with a diameter in the range of 30–150 nm. Their use has gained great momentum recently …

[HTML][HTML] Current perspectives on clinical use of exosomes as novel biomarkers for cancer diagnosis

X Yi, J Chen, D Huang, S Feng, T Yang, Z Li… - Frontiers in …, 2022 - frontiersin.org
Exosomes are a heterogeneous subset of extracellular vesicles (EVs) that biogenesis from
endosomes. Besides, exosomes contain a variety of molecular cargoes including proteins …

Extracellular Vesicles as Delivery Shippers for Noncoding RNA‐Based Modulation of Angiogenesis: Insights from Ischemic Stroke and Cancer

Y Pan, Y Liu, W Wei, X Yang, Z Wang, W Xin - Small, 2023 - Wiley Online Library
Ischemic stroke and systemic cancer are two of the leading causes of mortality. Hypoxia is a
central pathophysiological component in ischemic stroke and cancer, representing a joint …