Nitrone chemistry has been widely developed for a long time and many reviews have
outlined its rich transformation chemistry. However, most of these reviews involve …

The fluorine atom plays an important role in medicinal chemistry because fluorine
substitution has a strong impact on the physical, chemical, and biological properties of …

The mechanism of zw-type [3+ 2] cycloaddition (32CA) reactions of nitrones with electron-
deficient (ED) ethylenes has been studied using density functional theory (DFT) methods at …

Azidation (TMSN3, SnCl4) of a 9: 1 mixture of trans-and cis-5-acetoxy-2-methylisoxazolidin-
3-yl-3-phosphonates at the anomeric carbon atom led to the formation of the equimolar …

Detailed experimental and computational studies of the nitrone 3, 3‐dimethyl‐6‐phenyl‐2, 3‐
dihydro‐1, 2, 4‐triazin‐4‐oxide (2), which is a cyclized product of an open‐chain isomer 2 …

A spiro‐pyrrolidine‐catalyzed tandem aza‐1, 4‐addition/hemi‐acetalization reaction was
developed with excellent enantioselectivity (12 examples of≥ 99% ee), and several …

This review is focused on the synthesis of isoxazolidines as the core of biologically active
compounds having anti-cancer, antiviral, antibacterial and anti-inflammatory properties. The …

The azanucleosides are nucleoside analogues where the furanose ring is replaced by a
nitrogen‐containing ring or chain. Many azanucleosides are potent antiviral, anticancer and …

A synthetic approach towards a series of 3-hydroxymethyl-5-(1H-1, 2, 3-triazol)
isoxazolidines has been reported, according to a procedure based on the cycloaddition …

Homonucleoside analogues cis-16 and trans-17 having a (5-methoxycarbonyl)
isoxazolidine framework were synthesized via the 1, 3-dipolar cycloaddition of nucleobase …