[HTML][HTML] Gallbladder cancer epidemiology, pathogenesis and molecular genetics: Recent update

A Sharma, KL Sharma, A Gupta, A Yadav… - World journal of …, 2017 - ncbi.nlm.nih.gov
Gallbladder cancer is a malignancy of biliary tract which is infrequent in developed countries
but common in some specific geographical regions of developing countries. Late diagnosis …

Gallbladder cancer: lessons from a rare tumour

II Wistuba, AF Gazdar - Nature Reviews Cancer, 2004 - nature.com
Gallbladder cancer is a relatively rare form of malignancy about which our knowledge is
scant. However, a unique combination of predisposing factors—including genetic …

Preneoplastic lesions in gallbladder cancer

I Roa, X De Aretxabala, JC Araya… - Journal of surgical …, 2006 - Wiley Online Library
Background Gallbladder cancer is an uncommon disease except in countries like Chile and
areas of India and Japan. The knowledge regarding the etiology and mechanisms through …

Pathologies of precursor lesions of biliary tract carcinoma

Y Nakanuma, Y Kakuda, T Sugino, Y Sato, Y Fukumura - Cancers, 2022 - mdpi.com
Simple Summary Carcinomas and precursor lesions of the biliary tract belong to a spectrum
of pancreatobiliary neoplasms that share common histology and cell lineages. High-grade …

Genetic alteration and gene expression modulation during cancer progression

C Garnis, TPH Buys, WL Lam - Molecular Cancer, 2004 - Springer
Cancer progresses through a series of histopathological stages. Progression is thought to
be driven by the accumulation of genetic alterations and consequently gene expression …

Gallbladder cancer: current insights in genetic alterations and their possible therapeutic implications

H Kuipers, TJJ de Bitter, MT de Boer, RS van der Post… - Cancers, 2021 - mdpi.com
Simple Summary Knowledge of genetic alterations in gallbladder cancer (GBC) continues to
increase. This systematic review provides an overview of frequently occurring genetic …

Aberrant promoter hypermethylation of multiple genes in gallbladder carcinoma and chronic cholecystitis

T Takahashi, N Shivapurkar, E Riquelme… - Clinical Cancer …, 2004 - AACR
Purpose: Aberrant methylation of 5′ gene promoter regions is an epigenetic phenomenon
that is a major mechanism for silencing of tumor suppressor genes in many cancer types …

Chromosomal instability in gastric cancer: role in tumor development, progression, and therapy

MV Nemtsova, EB Kuznetsova, IV Bure - International Journal of …, 2023 - mdpi.com
According to the Cancer Genome Atlas (TCGA), gastric cancers are classified into four
molecular subtypes: Epstein–Barr virus-positive (EBV+), tumors with microsatellite instability …

[HTML][HTML] A genetic model for gallbladder carcinogenesis and its dissemination

SG Barreto, A Dutt, A Chaudhary - Annals of oncology, 2014 - Elsevier
Gallbladder cancer, although regarded as the most common malignancy of the biliary tract,
continues to be associated with a dismal overall survival even in the present day. While …

Mutation Spectrum of the 9q34 Tuberous Sclerosis Gene TSC1 in Transitional Cell Carcinoma of the Bladder

MA Knowles, T Habuchi, W Kennedy… - Cancer research, 2003 - AACR
Deletions of the long arm of chromosome 9 are the most common genetic alteration in
transitional cell carcinoma (TCC) of the bladder. Several regions of deletion on 9q have …