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Continuous communication between cells is necessary for development of any multicellular
organism and depends on the recognition of secreted signals. A wide range of molecules …

New normal linear modeling strategies are presented for analyzing read counts from RNA-
seq experiments. The voom method estimates the mean-variance relationship of the log …

For most problems in science and engineering we can obtain data sets that describe the
observed system from various perspectives and record the behavior of its individual …

Genome-wide association studies of human personality have been carried out, but
transcription of the whole genome has not been studied in relation to personality in humans …

Abstract dictyBase (http://dictybase. org), the model organism database for Dictyostelium
discoideum, includes the complete genome sequence and expression data for this …

The cortical patterning principle has been a long-standing question in neuroscience, yet
how this translates to macroscale functional specialization in the human brain remains …

Lamins are nuclear intermediate filament proteins with important, well-established roles in
humans and other vertebrates. Lamins interact with DNA and numerous proteins at the …

Terpenes are structurally diverse natural products involved in many ecological interactions.
The pivotal enzymes for terpene biosynthesis, terpene synthases (TPSs), had been …

Blebs and F-actin–driven pseudopods are alternative ways of extending the leading edge of
migrating cells. We show that Dictyostelium cells switch from using predominantly …