Although it has been widely applied in identification of genes responsible for biomedically,
economically, or even evolutionarily important complex and quantitative traits, traditional …

Evidence from many sources suggests that similar phenotypes are begotten by functionally
related genes. This is most obvious in the case of genetically heterogeneous diseases such …

Finding the most promising genes among large lists of candidate genes has been defined
as the gene prioritization problem. It is a recurrent problem in genetics in which genetic …

Abstract E ndeavour (http://www. esat. kuleuven. be/endeavourweb; this web site is free and
open to all users and there is no login requirement) is a web resource for the prioritization of …

The genomic era has been characterised by vast amounts of data from diverse sources,
creating a need for new tools to extract biologically meaningful information. Bioinformatics is …

The identification of genes involved in human hereditary diseases often requires the time‐
consuming and expensive examination of a great number of possible candidate genes …

One of the most important tasks of modern bioinformatics is the development of
computational tools that can be used to understand and treat human disease. To date, a …

Background Even in the post-genomic era, the identification of candidate genes within loci
associated with human genetic diseases is a very demanding task, because the critical …

The how's and why's of successful drug repositioning Drug repositioning, also known as
drug reprofiling or repurposing, has become an increasingly important part of the drug …

Background With the global spread of multidrug resistance in pathogenic microbes,
infectious diseases emerge as a key public health concern of the recent time. Identification …