[HTML][HTML] The G· U wobble base pair

G Varani, WH McClain - EMBO reports, 2000 - embopress.org
The G· U wobble base pair is a fundamental unit of RNA secondary structure that is present
in nearly every class of RNA from organisms of all three phylogenetic domains. It has …

The accuracy of ribosomal RNA comparative structure models

RR Gutell, JC Lee, JJ Cannone - Current opinion in structural biology, 2002 - Elsevier
The determination of the 16S and 23S rRNA secondary structure models was initiated
shortly after the first complete 16S and 23S rRNA sequences were determined in the late …

Crystal structure of a group I ribozyme domain: principles of RNA packing

JH Cate, AR Gooding, E Podell, K Zhou, BL Golden… - Science, 1996 - science.org
Group I self-splicing introns catalyze their own excision from precursor RNAs by way of a two-
step transesterification reaction. The catalytic core of these ribozymes is formed by two …

Small RNAs with imperfect match to endogenous mRNA repress translation: implications for off-target activity of small inhibitory RNA in mammalian cells

S Saxena, ZO Jónsson, A Dutta - Journal of Biological Chemistry, 2003 - ASBMB
A 21-base pair RNA duplex that perfectly matches an endogenous target mRNA selectively
degrades the mRNA and suppresses gene expression in mammalian tissue culture cells. A …

Investigation of the Structural Basis for Thermodynamic Stabilities of Tandem GU Mismatches:  Solution Structure of (rGAGGUCUC)2 by Two-Dimensional NMR and Simulated …

JA McDowell, DH Turner - Biochemistry, 1996 - ACS Publications
The duplex (rGAG GU CUC) 2 contains the motif which is unusually stable compared with
other symmetric tandem GU mismatches and occurs in the P5 helix of the group I intron of …

[HTML][HTML] Metals, motifs, and recognition in the crystal structure of a 5S rRNA domain

CC Correll, B Freeborn, PB Moore, TA Steitz - Cell, 1997 - cell.com
Two new RNA structures portray how non-Watson-Crick base pairs and metal ions can
produce a unique RNA shape suitable for recognition by proteins. The crystal structures of a …

[图书][B] DNA and RNA modification enzymes: structure, mechanism, function and evolution

H Grosjean - 2009 - taylorfrancis.com
This volume is a timely and comprehensive description of the many facets of DNA and RNA
modification-editing processes and to some extent repair mechanisms. Each chapter offers …

Metal-binding sites in the major groove of a large ribozyme domain

JH Cate, JA Doudna - Structure, 1996 - cell.com
Background Group I self-splicing introns catalyze sequential transesterification reactions
within an RNA transcript to produce the correctly spliced product. Often several hundred …

Conservation and tissue-specific transcription patterns of long noncoding RNAs

M Ward, C McEwan, JD Mills… - Journal of human …, 2015 - Taylor & Francis
Over the past decade, the focus of molecular biology has shifted from being predominately
DNA and protein-centric to having a greater appreciation of RNA. It is now accepted that the …

Stitching together RNA tertiary architectures

T Hermann, DJ Patel - Journal of molecular biology, 1999 - Elsevier
The powerful explanatory paradigm of molecular biology requiring form to co-evolve with
function has again been proven successful when, over the recent two decades, a wealth of …