In contrast to non-canonical ligands, canonical Wnts promote the stabilization of β-catenin,
which is a prerequisite for formation of the TCF4/β-catenin transcriptional complex and …

The POZ-ZF transcription factor Kaiso was discovered two decades ago as a binding partner
for p120 ctn. Since its discovery, roles for Kaiso in diverse biological processes (epithelial-to …

CP190 is a co-factor in many Drosophila architectural proteins, being involved in the
formation of active promoters and insulators. CP190 contains the N-terminal BTB/POZ …

Background There has been a notable increase in interest in the transcriptional regulator
Kaiso, which has been linked to the regulation of clonal hematopoiesis, myelodysplastic …

Gain and loss of DNA methylation in cells is a dynamic process that tends to achieve an
equilibrium. Many factors are involved in maintaining the balance between DNA methylation …

The tripartite motif (TRIM) family proteins are a group of proteins involved in different
signaling pathways. The changes in the expression regulation, function, and signaling of this …

Our previous work had confirmed that pyruvate kinase L/R (PKLR) gene was expressed
differently in different lactation periods of dairy cattle, and participated in lipid metabolism …

Epigenetic regulation refers to the alteration of gene expression independent of changes in
DNA sequence. It involves chemical modifications such as DNA methylation, histone …

DNA methylation is the most important epigenetic modification involved in the regulation of
transcription, imprinting, establishment of X-inactivation, and the formation of a chromatin …

Kaiso is a methyl DNA binding transcriptional factor involved in cell cycle control, WNT
signaling, colon inflammation, and cancer progression. Recently, it was shown that …