LSECs are a unique population of endothelial cells within the liver and are recognized as
key regulators of liver homeostasis. LSECs also play a key role in liver disease, as …

Non-alcoholic fatty liver disease (NAFLD) is considered as the hepatic manifestation of
metabolic syndrome, which is characterised by obesity, insulin resistance …

Liver fibrosis due to viral or metabolic chronic liver diseases is a major challenge of global
health. It is a critical pre-stage condition of severe hepatopathy, characterized by excessive …

The increasing prevalence of the metabolic syndrome (MetS) is a threat to global public
health due to its lethal complications. Nonalcoholic fatty liver disease (NAFLD) is the hepatic …

Simple Summary Hepatocellular carcinoma (HCC) associated with portal vein thrombosis
(PVT) represents an advanced stage of the tumor, with a subsequently poor prognosis and …

Liver sinusoidal endothelial cells (LSECs) are key players in maintaining hepatic
homeostasis. They also play crucial roles during liver injury by communicating with liver cell …

Nonalcoholic steatohepatitis (NASH) and alcoholic hepatitis (AH) affect a large part of the
general population worldwide. Dysregulation of lipid metabolism and alcohol toxicity drive …

The liver lymphatic system is essential for maintaining tissue fluid balance and immune
function. The detailed structure of lymphatic vessels (LVs) in the liver remains to be fully …

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive lung disease, but its
pathogenesis is still unclear. Bioinformatics methods were used to explore the differentially …

The hepatic sinusoids are composed of liver sinusoidal endothelial cells (LSEC), which are
surrounded by hepatic stellate cells (HSC) and contain liver-resident macrophages called …