In this review, the history of boron's early use in drugs, and the history of the use of boron functional groups in medicinal chemistry applications are discussed. This includes …
Advances in the field of boron chemistry have expanded the application of this element in Medicinal Chemistry. Boron-containing compounds represent a new class for medicinal …
The incorporation of the “magic” boron atom has been established as an important new strategy in the field of medicinal chemistry as boron compounds have been shown to form …
The unique electron deficiency and coordination property of boron led to a wide range of applications in chemistry, energy research, materials science and the life sciences. The use …
KS Romero-Aguilar, IM Arciniega-Martínez… - Expert Opinion on …, 2019 - Taylor & Francis
Introduction: Boron-containing compounds induce effects on immune responses. Such effects are interesting to the biomedical field for the development of therapeutic tools to …
GV Rigo, LA Frank, GB Galego, ALS Santos, T Tasca - Venereology, 2022 - mdpi.com
The multistep translational science behind new drugs comprehends the entire process through laboratory, clinical, and community observations turned into health interventions …
V Adimule, AH Jagadeesha Gowda… - … for Malaria: Novel …, 2022 - Wiley Online Library
In the present research, series of 1, 3‐bezoxoborole containing 1, 3, 4‐oxadiazole compounds was designed and synthesised by microwave cyclisation (MWC) using 1, 3 …
AI Zulu, OO Oderinlo, C Kruger, M Isaacs, HC Hoppe… - Molecules, 2020 - mdpi.com
With an intention of identifying chalcone derivatives exhibiting anti-protozoal activity, a cohort of relatively unexplored arylpyrrole-based chalcone derivatives were synthesized in …
Herein we report the synthesis of 21 novel small molecules inspired by metronidazole and Schiff base compounds. The compounds were evaluated against Trichomonas vaginalis …