The connection between epithelial-mesenchymal (EM) plasticity and cancer stem cell (CSC)
properties has been paradigm-shifting, linking tumor cell invasion and metastasis with …

Breast cancer (BC) is the leading cause of cancer-related mortality in women, only followed
by lung cancer. Given the importance of BC in public health, it is essential to identify …

Neoadjuvant treatment offers a number of benefits for patients with early breast cancer, and
is an important option for consideration by multidisciplinary teams. Despite literature …

Recently, Simvastatin (SIM) is received notable attention due to its anti-cancer properties.
However, the lipophilicity feature of SIM restricted its application as a chemotherapy agent …

Patients with locally advanced breast cancer have a worse prognosis compared to patients
with localized tumors and require neoadjuvant treatment before surgery. The aim of this …

Breast cancer is the most common cancer in women, with more than 1.7 million diagnoses
worldwide per annum. Metastatic breast cancer remains incurable, and the presence of …

Cancer is a disease that affects and kills millions of people worldwide. Breast cancer,
especially, has a high incidence and mortality, and is challenging to treat. Due to its high …

Breast cancer is the most common cancer diagnosed in women worldwide. Although a
series of treatment options have improved the overall 5-year survival rate to 90%, individual …

Purpose Several studies have evaluated the role of delayed initiation of adjuvant
chemotherapy (AC) in breast cancer (BC), but the results have remained controversial and …

Triple negative breast cancer [TNBC] cells are reported to secrete the neurotrophin nerve
growth factor [NGF] and express its receptors, p75 neurotrophin receptor [p75 NTR] and …