Can we reduce the incidence of second primary malignancies occurring after radiotherapy? A critical review

M Tubiana - Radiotherapy and Oncology, 2009 - Elsevier
Second primary malignancies (SPMs) occurring after oncological treatment have become a
major concern during the past decade. Their incidence has long been underestimated …

Systemic mechanisms and effects of ionizing radiation: A new⿿ old⿿ paradigm of how the bystanders and distant can become the players

Z Nikitaki, IV Mavragani, DA Laskaratou, V Gika… - Seminars in cancer …, 2016 - Elsevier
Exposure of cells to any form of ionizing radiation (IR) is expected to induce a variety of DNA
lesions, including double strand breaks (DSBs), single strand breaks (SSBs) and oxidized …

Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer's models

MV Lourenco, RL Frozza, GB de Freitas, H Zhang… - Nature medicine, 2019 - nature.com
Defective brain hormonal signaling has been associated with Alzheimer's disease (AD), a
disorder characterized by synapse and memory failure. Irisin is an exercise-induced …

The Linear No-Threshold Relationship Is Inconsistent with Radiation Biologic and Experimental Data1

M Tubiana, LE Feinendegen, C Yang, JM Kaminski - Radiology, 2009 - pubs.rsna.org
The carcinogenic risk induced by low doses of ionizing radiation is controversial. It cannot
be assessed with epidemiologic methods alone because at low doses the data are …

Key mechanisms involved in ionizing radiation-induced systemic effects. A current review

IV Mavragani, DA Laskaratou, B Frey… - Toxicology …, 2016 - academic.oup.com
Organisms respond to physical, chemical and biological threats by a potent inflammatory
response, aimed at preserving tissue integrity and restoring tissue homeostasis and …

History of bystander effects research 1905-present; what is in a name?

C Mothersill, A Rusin… - … journal of radiation …, 2018 - Taylor & Francis
Purpose: This review, which arose from a Radiation Research Society History symposium,
traces the history of 'bystander effects' or 'indirect effects'(also known as 'abscopal …

Does scientific evidence support a change from the LNT model for low-dose radiation risk extrapolation?

D Averbeck - Health physics, 2009 - journals.lww.com
The linear no-threshold (LNT) model has been widely used to establish international rules
and standards in radiation protection. It is based on the notion that the physical energy …

Hormesis and epigenetics: is there a link?

AM Vaiserman - Ageing research reviews, 2011 - Elsevier
Epigenetic regulation of gene expression is a key molecular mechanism linking
environmental factors with the genome with consequences for health status throughout the …

Home and away: the role of non-coding RNA in intracellular and intercellular DNA damage response

A Shaw, M Gullerova - Genes, 2021 - mdpi.com
Non-coding RNA (ncRNA) has recently emerged as a vital component of the DNA damage
response (DDR), which was previously believed to be solely regulated by proteins. Many …

iTRAQ analysis of gill proteins from the zebrafish (Danio rerio) infected with Aeromonas hydrophila

A Lü, X Hu, Y Wang, X Shen, X Li, A Zhu, J Tian… - Fish & shellfish …, 2014 - Elsevier
The gills are large mucosal surfaces and very important portals for pathogen entry in fish.
The aim of this study was to determine the gill immune response at the protein levels, the …