Safety of COVID-19 vaccines in patients with autoimmune diseases, in patients with cardiac issues, and in the healthy population

L Frasca, G Ocone, R Palazzo - Pathogens, 2023 - mdpi.com
The coronavirus disease 2019 (COVID-19) has been a challenge for the whole world since
the beginning of 2020, and COVID-19 vaccines were considered crucial for disease …

New insights gained from cellular landscape changes in myocarditis and inflammatory cardiomyopathy

W Wang, H Jia, X Hua, J Song - Heart Failure Reviews, 2024 - Springer
Advances in the etiological classification of myocarditis and inflammatory cardiomyopathy
(ICM) have reached a consensus. However, the mechanism of myocarditis/ICM remains …

Self-DNA driven inflammation in COVID-19 and after mRNA-based vaccination: lessons for non-COVID-19 pathologies

M Heil - Frontiers in Immunology, 2024 - frontiersin.org
The coronavirus disease 2019 (COVID-19) pandemic triggered an unprecedented
concentration of economic and research efforts to generate knowledge at unequalled speed …

Single-cell RNA sequencing reveals characteristics of myeloid cells in pulmonary post-acute sequelae of SARS-CoV-2

H Yoon, LS Dean, B Jiyarom, V Khadka, Y Deng… - bioRxiv, 2023 - biorxiv.org
Background Although our understanding of the immunopathology and subsequent risk and
severity of COVID-19 disease is evolving, a detailed account of immune responses that …

Epigenomic landscape exhibits interferon signaling suppression in the patient of myocarditis after BNT162b2 vaccination

H Kim, HS Ahn, N Hwang, Y Huh, S Bu, KJ Seo… - Scientific Reports, 2023 - nature.com
After the outbreak of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
pandemic, a novel mRNA vaccine (BNT162b2) was developed at an unprecedented speed …

A distinct immune landscape in anti-synthetase syndrome profiled by a single-cell genomic study

J Ding, Y Li, Z Wang, F Han, M Chen, J Du… - Frontiers in …, 2024 - frontiersin.org
Objectives The objective of this study was to profile the transcriptional profiles of peripheral
blood mononuclear cells (PBMCs) and their immune repertoires affected by anti-synthetase …

Identification of Host PDZ-Based Interactions with the SARS-CoV-2 E Protein in Human Monocytes

A Ávila-Flores, JJ Sánchez-Cabezón… - International Journal of …, 2023 - mdpi.com
Proteins containing PDZ (post-synaptic density, PSD-95/disc large, Dlg/zonula occludens,
ZO-1) domains assemble signaling complexes that orchestrate cell responses. Viral …

Role of immune cells in the pathogenesis of myocarditis

K Liu, B Han - Journal of Leukocyte Biology, 2024 - academic.oup.com
Myocarditis is an inflammatory heart disease that mostly affects young people. Myocarditis
involves a complex immune network; however, its detailed pathogenesis is currently …

Monocytic reactive oxygen species-induced T cell apoptosis impairs cellular immune response to SARS-CoV-2 mRNA vaccine

S Gimenez, E Hamrouni, S André, M Picard… - Journal of Allergy and …, 2025 - Elsevier
Background We have recently shown that, during acute severe COVID-19, SARS-CoV-2
spike protein (S) induces a cascade of events resulting in T cell apoptosis. Indeed, by …