The hydrotropy though existing as precisely used scientific approach assisting solubilization
for all. It took 66 long years to use the concept in drug analysis since its inception in 1916 …

Nonsteroidal anti-inflammatory drugs (NSAIDs) are the first choice of treatment for rheumatic
disorders and other degenerative inflammatory diseases. One of them, indomethacin …

Hydrotropic solubilization is a technique that can be used to improve the solubility of drugs
that are poorly soluble. This technique involves adding a large amount of a second solute …

Objective: The aim of this study is to prepare floating hollow microspheres encapsulating
Sorafenib (SFN) to enhance its oral bioavailability. Methods: Gastro-floating hollow adhesive …

This review explores sustainable strategies for enhancing the solubility of poorly water-
soluble pharmaceutical active ingredients (PAIs), focusing on hydrotropy and co-solvency …

This research aims to develop methods for simultaneously determining indomethacin (IND)
and nicotinamide (NCT) in binary mixtures, immediate‐release capsules, sustained‐release …

In present research work a new simple, specific, precise, accurate, robust and economical
UV-Spectrophotometric method for simultaneous estimation of ofloxacin and ornidazole in …

Two simple, rapid and inexpensive spectrophotometric methods were proposed for the
determination of indomethacin in its pure form, pharmaceutical formulations and in the …

An acceptable, safe, and green technique for solubilization of poorly soluble drugs is the
major important initial step for their handling through analytical work. Various procedures …

The dominance of searching for water‐soluble drugs in drug discovery has radically
amplified the obstacles. Although poorly soluble drugs signify a class of active …