Patients with chronic HBV infection are at risk of reactivation of HBV should they require
immunosuppressive therapies for a variety of clinical settings, including chemotherapy for …

Currently, the indications to perform reduced-intensity conditioning allogeneic hematopoietic
stem cell transplant (RIC-HCT) are based on data derived mainly from large registry and …

NK cell exhaustion (NCE) due to sustained proliferation results in impaired NK cell function
with loss of cytokine production and lytic activity. Using murine models of chronic NK cell …

The use of umbilical cord blood (UCB) as an alternative haematopoietic cell source in lieu of
bone marrow for haematopoietic reconstitution is increasingly becoming a mainstay …

Hematopoietic stem cell transplantation (HSCT) is one of a range of therapeutic options
available to patients suffering from various diseases. HSCT procedure involves important …

Immunocompetent hosts are estimated to inhale hundreds of fungal conidia daily, but most
fungal pathogens are cleared without development of clinical infection. 1, 2 By contrast …

Background: We performed a systematic review and meta-analysis to compare the clinical
outcomes and toxicity of reduced-intensity conditioning (RIC) and myeloablative …

Transfusion medicine plays a vital role in the supportive care of patients receiving therapy
for hematology, oncology and hematopoietic stem cell transplants (HSCT). With advances in …

Hematopoietic cell transplantation (HCT) serves to repopulate the recipient's hematopoietic
and immune system with donor-derived cells. Donor-derived macrophages reside in various …

The conditioning regimens used for the allo-HSCT include either myeloablative conditioning
(MAC) or reduced intensity conditioning (RIC) regimens based on the age, performance …