Novel agents for the pharmacological treatment of alcohol use disorder

EM Burnette, SJ Nieto, EN Grodin, LR Meredith… - Drugs, 2022 - Springer
Alcohol use disorder (AUD) is a highly prevalent but severely under-treated disorder, with
only three widely-approved pharmacotherapies. Given that AUD is a very heterogeneous …

Crossing the blood–brain barrier: recent advances in drug delivery to the brain

MM Patel, BM Patel - CNS drugs, 2017 - Springer
CNS disorders are on the rise despite advancements in our understanding of their
pathophysiological mechanisms. A major hurdle to the treatment of these disorders is the …

Drug addiction: hyperkatifeia/negative reinforcement as a framework for medications development

GF Koob, R Dantzer - Pharmacological reviews, 2021 - Elsevier
Compulsive drug seeking that is associated with addiction is hypothesized to follow a
heuristic framework that involves three stages (binge/intoxication, withdrawal/negative affect …

[图书][B] The psychology of religion: An empirical approach

RW Hood Jr, PC Hill, B Spilka - 2009 - books.google.com
Scholarly and comprehensive yet accessible, this state-of-the-science work is widely
regarded as the definitive graduate-level psychology of religion text. The authors synthesize …

State-of-the-art behavioral and pharmacological treatments for alcohol use disorder

LA Ray, S Bujarski, E Grodin, E Hartwell… - The American journal …, 2019 - Taylor & Francis
Background: Alcohol use disorder (AUD) and its associated consequences remain
significant public health concerns. Given that AUD represents a spectrum of severity …

Translational opportunities in animal and human models to study alcohol use disorder

SJ Nieto, EN Grodin, CG Aguirre, A Izquierdo… - Translational …, 2021 - nature.com
Animal and human laboratory paradigms offer invaluable approaches to study the complex
etiologies and mechanisms of alcohol use disorder (AUD). We contend that human …

Consideration of sex and gender differences in addiction medication response

SA McKee, AL McRae-Clark - Biology of sex Differences, 2022 - Springer
Substance use continues to contribute to significant morbidity and mortality in the United
States, for both women and men, more so than any other preventable health condition. To …

[HTML][HTML] Alcohol use disorder: the role of medication in recovery

BJ Mason, CJ Heyser - Alcohol Research: Current Reviews, 2021 - ncbi.nlm.nih.gov
The misuse of alcohol in the United States continues to take a large toll on society, resulting
in the deaths of about 88,000 Americans per year. Moreover, it is estimated that nearly 14.6 …

Is AD a stress-related disorder? Focus on the HPA axis and its promising therapeutic targets

G Canet, C Hernandez, C Zussy… - Frontiers in aging …, 2019 - frontiersin.org
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that has important
health and economic impacts in the elderly. Despite a better understanding of the molecular …

Medications for alcohol use disorders: An overview

M Akbar, M Egli, YE Cho, BJ Song… - Pharmacology & …, 2018 - Elsevier
Patients who suffer from alcohol use disorders (AUDs) usually go through various socio-
behavioral and pathophysiological changes that take place in the brain and other organs …