Induction of oxidative stress and human leukocyte/endothelial cell interactions in polycystic ovary syndrome patients with insulin resistance

VM Victor, M Rocha, C Banuls, A Alvarez… - The Journal of …, 2011 - academic.oup.com
Context: Insulin resistance is a feature of polycystic ovary syndrome (PCOS) and is related to
mitochondrial and endothelial function. Objective: We tested whether hyperandrogenic …

Metabolic hormones modulate macrophage inflammatory responses

MJ Batty, G Chabrier, A Sheridan, MC Gage - Cancers, 2021 - mdpi.com
Simple Summary Macrophages are a type of immune cell which play an important role in the
development of cancer. Obesity increases the risk of cancer and obesity also causes …

[PDF][PDF] Role of proton pump inhibitors in preventing hypergastrinemia-associated carcinogenesis and in antagonizing the trophic effect of gastrin

YM Han, JM Park, N Kangwan, M Jeong, S Lee… - J Physiol …, 2015 - jpp.krakow.pl
Gastrin is the main hormone stimulating gastric acid secretion, but it exerts proliferative and
anti-apoptotic actions on various cancer cell types, in addition to its well-known trophic effect …

Human leukocyte/endothelial cell interactions and mitochondrial dysfunction in type 2 diabetic patients and their association with silent myocardial ischemia

A Hernandez-Mijares, M Rocha, S Rovira-Llopis… - Diabetes …, 2013 - Am Diabetes Assoc
OBJECTIVE Diabetes is associated with oxidative stress and increased mortality, but a
possible correlation between leukocyte-endothelium interactions, oxidative stress, and silent …

The Gastric Connection: Serum Gastric Biomarkers, Metabolic Syndrome and Transition in Metabolic Status

Y Qin, S Yao, G Wang, Z Xu, G Zhu, Y Li… - Journal of …, 2024 - Taylor & Francis
Objective Inflammation plays a crucial role in the development of metabolic syndrome
(MetS). However, the roles of pepsinogens (PGs) and gastrin, known biomarkers linked to …

[HTML][HTML] Differential effects of anti-TNF-α and anti-IL-12/23 agents on human leukocyte–endothelial cell interactions

C Ríos-Navarro, C de Pablo, V Collado-Diaz… - European journal of …, 2015 - Elsevier
Enhanced leukocyte recruitment is an inflammatory process that occurs during early phases
of the vascular dysfunction that characterises atherosclerosis. We evaluated the impact of …

Ectopic pregnancy as a model to identify endometrial genes and signaling pathways important in decidualization and regulated by local trophoblast

WC Duncan, JLV Shaw, S Burgess, SE McDonald… - PloS one, 2011 - journals.plos.org
The endometrium in early pregnancy undergoes decidualization and functional changes
induced by local trophoblast, which are not fully understood. We hypothesized that …

Abacavir and didanosine induce the interaction between human leukocytes and endothelial cells through Mac-1 upregulation

C De Pablo, S Orden, N Apostolova, A Blanquer… - Aids, 2010 - journals.lww.com
Objective: Abacavir and didanosine are nucleoside reverse transcriptase inhibitors (NRTI)
widely used in therapy for HIV-infection but which have been linked to cardiovascular …

Paradoxically Augmented Anti-Tumorigenic Action of Proton Pump Inhibitor and Gastrin in APCMin/+ Intestinal Polyposis Model1

YM Han, KB Hahm, JM Park, SP Hong, EH Kim - Neoplasia, 2014 - Elsevier
Though long-term administration of proton pump inhibitor (PPI) imposed the risk of
gastrointestinal track tumorigenesis by accompanied hypergastrinemia, no overt increases …

[HTML][HTML] Gastric mucosal immune profiling and dysregulation in idiopathic gastroparesis

A Gottfried-Blackmore, H Namkoong… - Clinical and …, 2021 - journals.lww.com
METHODS: In this cross-sectional prospective case-control study, routine endoscopic
biopsies were used for comprehensive immune profiling by flow cytometry, multicytokine …