DNA methylation is the most well studied of the epigenetic regulators in relation to
environmental exposures. To date, numerous studies have detailed the manner by which …

Lead toxicity is a major public health issue in developed and developing countries. Both
acute and chronic lead exposure has the potential to cause many deleterious systematic …

We report that the DNA methylation profile of a child's neonatal whole blood can be
significantly influenced by his or her mother's neonatal blood lead levels (BLL). We recruited …

Background DNA methylation (DNAm) is a potential mechanism for propagating the effects
of environmental exposures on child and adolescent mental health. In recent years, this field …

Many complex traits or diseases, such as infectious and autoimmune diseases, cancer,
xenobiotics exposure, neurodevelopmental and neurodegenerative diseases, as well as the …

Obesity is a complex and multifactorial disease, which likely comprises multiple subtypes.
Emerging data have linked chemical exposures to obesity. As organismal response to …

Background Dried blood spot (DBS) sampling is a simple, cost-effective, and minimally
invasive alternative to venipuncture for measuring exposure biomarkers in public health and …

Individuals born extremely preterm (before 28 weeks of gestation) comprise only about 0.7%
of births in the United States and an even lower proportion in other high resource countries …

Environmental lead (Pb) exposure is closely associated with pathogenesis of a range of
neurological disorders, including Alzheimer's disease (AD), Parkinson's disease (PD) …

Sex is a modulator of health that has been historically overlooked in biomedical research.
Recognizing this knowledge gap, funding agencies now mandate the inclusion of sex as a …