COVID, complement, and the brain

SI Vlaicu, A Tatomir, J Cuevas, V Rus… - Frontiers in …, 2023 - frontiersin.org
The brains of COVID-19 patients are affected by the SARS-CoV-2 virus, and these effects
may contribute to several COVID-19 sequelae, including cognitive dysfunction (termed “long …

COVID-19 and Alzheimer's Disease Share Common Neurological and Ophthalmological Manifestations: A Bidirectional Risk in the Post-Pandemic Future

G Amadoro, V Latina, E Stigliano, A Micera - Cells, 2023 - mdpi.com
A growing body of evidence indicates that a neuropathological cross-talk takes place
between the coronavirus disease 2019 (COVID-19)-the pandemic severe pneumonia that …

Posthospitalization COVID-19 cognitive deficits at 1 year are global and associated with elevated brain injury markers and gray matter volume reduction

GK Wood, BF Sargent, ZUA Ahmad, K Tharmaratnam… - Nature medicine, 2025 - nature.com
The spectrum, pathophysiology and recovery trajectory of persistent post-COVID-19
cognitive deficits are unknown, limiting our ability to develop prevention and treatment …

The kynurenine pathway relates to post‐acute COVID‐19 objective cognitive impairment and PASC

LA Cysique, D Jakabek, SG Bracken… - Annals of Clinical …, 2023 - Wiley Online Library
Objective To determine the prevalence and natural history of post‐acute COVID‐19
objective cognitive impairment and function, and their relationship to demographic, clinical …

Scientific rationale for the treatment of cognitive deficits from long COVID

A Fesharaki Zadeh, AFT Arnsten, M Wang - Neurology International, 2023 - mdpi.com
Sustained cognitive deficits are a common and debilitating feature of “long COVID”, but
currently there are no FDA-approved treatments. The cognitive functions of the dorsolateral …

[HTML][HTML] Cognitive impairment after recovery from COVID-19: frequency, profile, and relationships with clinical and laboratory indices

S Galderisi, A Perrottelli, L Giuliani, MA Pisaturo… - European …, 2024 - Elsevier
Cognitive impairment (CI) is regarded as a remarkable burden in COVID-19 survivors. Its
prevalence and profile, and relationships with the disease clinical and laboratory indices …

[HTML][HTML] Frequency and correlates of subjective cognitive complaints and objective cognitive screening results in African American adults following COVID-19 infection

FC Goldstein, I Hajjar, A Summers, AD Truong… - Brain, Behavior, & …, 2023 - Elsevier
Background Subjective cognitive complaints are frequent following COVID-19 infection, but
assessment of whether these complaints map onto objective cognitive findings may not be …

Cognitive impairments and mental health of patients with post-COVID-19: A cross-sectional study

E Morawa, J Krehbiel, A Borho, R Herold, M Lieb… - Journal of …, 2023 - Elsevier
Background Persistent cognitive complaints belong to the most frequent symptoms after
COVID-19. This study explored the neuropsychological profile, mental health and risk factors …

[HTML][HTML] The Leipzig Treatment Program for Interdisciplinary Diagnosis and Therapy of Neurocognitive Post-COVID Symptoms

AS Hasting, S Herzig, H Obrig… - Zeitschrift für …, 2023 - econtent.hogrefe.com
This study introduces a 3-week group program designed for patients with neurocognitive
post-COVID-19 syndrome (PCS). The program represents a combination of evidence-based …

Melatonin: a ferroptosis inhibitor with potential therapeutic efficacy for the post-COVID-19 trajectory of accelerated brain aging and neurodegeneration

A Yehia, OA Abulseoud - Molecular Neurodegeneration, 2024 - Springer
The unprecedented pandemic of COVID-19 swept millions of lives in a short period, yet its
menace continues among its survivors in the form of post-COVID syndrome. An …