The convergence of advances in medical science, human biology, data science, and
technology has enabled the generation of new insights into the phenotype known as …

Metformin is the most often prescribed drug for people with type 2 diabetes (T2D). More than
120 million patients with T2D use metformin worldwide. However, monotherapy fails to …

Mitochondria play a key role in cancer and their involvement is not limited to the production
of ATP only. Mitochondria also produce reactive oxygen species and building blocks to …

Advances in genomic technologies have led to a wealth of information identifying genetic
polymorphisms in membrane transporters, specifically how these polymorphisms affect drug …

Psoriasis is a common, chronic inflammatory skin disorder that occurs worldwide. However,
epidemiological, clinical, and therapeutic data pertaining to psoriasis in non-Caucasian …

The incidence of youth type 2 diabetes (T2D), linked with obesity and declining physical
activity in high‐risk populations, is increasing. Recent multicenter studies have led to a …

This article is a narrative review of the epidemiological data available on diabetes
prevalence and care and of studies indexed in PubMed involving trials that evaluated …

Despite its widespread use as the first-line agent for the treatment of type 2 diabetes, it has
become clear that metformin does not work optimally for everyone. Elucidating who are the …

The continued global increase in the prevalence of obesity prompted a meeting at the Royal
Society of London investigating causal mechanisms of the disease,'Causes of obesity …

What is known and objective Metformin has received increasing attention owing to its
potential protective effect against cancer. We aimed to summarize evidence regarding the …