Bridging the gap between connectome and transcriptome
The recent construction of brain-wide gene expression atlases, which measure the
transcriptional activity of thousands of genes in multiple anatomical locations, has made it …
transcriptional activity of thousands of genes in multiple anatomical locations, has made it …
[HTML][HTML] Where the genome meets the connectome: understanding how genes shape human brain connectivity
The integration of modern neuroimaging methods with genetically informative designs and
data can shed light on the molecular mechanisms underlying the structural and functional …
data can shed light on the molecular mechanisms underlying the structural and functional …
A transcriptional signature of hub connectivity in the mouse connectome
BD Fulcher, A Fornito - … of the National Academy of Sciences, 2016 - National Acad Sciences
Connectivity is not distributed evenly throughout the brain. Instead, it is concentrated on a
small number of highly connected neural elements that act as network hubs. Across different …
small number of highly connected neural elements that act as network hubs. Across different …
Gene transcription profiles associated with inter-modular hubs and connection distance in human functional magnetic resonance imaging networks
Human functional magnetic resonance imaging (fMRI) brain networks have a complex
topology comprising integrative components, eg long-distance inter-modular edges, that are …
topology comprising integrative components, eg long-distance inter-modular edges, that are …
Overcoming false-positive gene-category enrichment in the analysis of spatially resolved transcriptomic brain atlas data
Transcriptomic atlases have improved our understanding of the correlations between gene-
expression patterns and spatially varying properties of brain structure and function. Gene …
expression patterns and spatially varying properties of brain structure and function. Gene …
Differential gene expression between callosal and ipsilateral projection neurons in the monkey dorsolateral prefrontal and posterior parietal cortices
D Arion, JF Enwright, G Gonzalez-Burgos… - Cerebral …, 2023 - academic.oup.com
Reciprocal connections between primate dorsolateral prefrontal (DLPFC) and posterior
parietal (PPC) cortices, furnished by subsets of layer 3 pyramidal neurons (PNs), contribute …
parietal (PPC) cortices, furnished by subsets of layer 3 pyramidal neurons (PNs), contribute …
[HTML][HTML] Uncovering the transcriptional correlates of hub connectivity in neural networks
Connections in nervous systems are disproportionately concentrated on a small subset of
neural elements that act as network hubs. Hubs have been found across different of species …
neural elements that act as network hubs. Hubs have been found across different of species …
Overcoming bias in gene-set enrichment analyses of brain-wide transcriptomic data
The recent availability of whole-brain atlases of gene expression, which quantify the
transcriptional activity of thousands of genes across many different brain regions, has …
transcriptional activity of thousands of genes across many different brain regions, has …
Exploiting gene expression profiles for the automated prediction of connectivity between brain regions
The brain comprises a complex system of neurons interconnected by an intricate network of
anatomical links. While recent studies demonstrated the correlation between anatomical …
anatomical links. While recent studies demonstrated the correlation between anatomical …
Neuronal activities in the mouse visual cortex predict patterns of sensory stimuli
Visual cortex forms the basis of visual processing and plays important roles in visual
encoding. By using the recently published Allen Brain Observatory dataset consisting of …
encoding. By using the recently published Allen Brain Observatory dataset consisting of …