[HTML][HTML] Alcohol Use Disorder and Dementia: A Review

NM Zahr - Alcohol Research: Current Reviews, 2024 - ncbi.nlm.nih.gov
PURPOSE By 2040, 21.6% of Americans will be over age 65, and the population of those
older than age 85 is estimated to reach 14.4 million. Although not causative, older age is a …

Acute and chronic ethanol effects during adolescence on neuroimmune responses: consequences and potential pharmacologic interventions

KN Nwachukwu, HE Mohammed, DQR Mebane… - Cells, 2023 - mdpi.com
Heavy ethanol consumption during adolescence has been linked to neuroimmune response
dysregulation and cognitive deficits in the developing adolescent brain. During …

Age-dependent dysregulation of locus coeruleus firing in a transgenic rat model of Alzheimer's disease

MA Kelberman, JM Rorabaugh, CR Anderson… - Neurobiology of …, 2023 - Elsevier
Hyperphosphorylated tau in the locus coeruleus (LC) is ubiquitous in prodromal Alzheimer's
disease (AD), and LC neurons degenerate as AD progresses. Hyperphosphorylated tau …

Bioinformatics analysis and prediction of Alzheimer's disease and alcohol dependence based on Ferroptosis-related genes

M Tian, J Shen, Z Qi, Y Feng, P Fang - Frontiers in aging …, 2023 - frontiersin.org
Background Alzheimer's disease (AD) is a neurodegenerative disease whose origins have
not been universally accepted. Numerous studies have demonstrated the relationship …

[HTML][HTML] Diversity of ancestral brainstem noradrenergic neurons across species and multiple biological factors

MA Kelberman, E Rodberg, E Arabzadeh… - …, 2024 - pmc.ncbi.nlm.nih.gov
The brainstem region, locus coeruleus (LC), has been remarkably conserved across
vertebrates. Evolution has woven the LC into wide-ranging neural circuits that influence …

Oral Fentanyl Consumption Alters Sleep Rhythms, Promotes Avoidance Behaviors, Impairs Fear Extinction Learning, and Alters Basolateral Amygdala Physiology in …

AM Downs, G Kmiec, ZA McElligott - bioRxiv, 2023 - biorxiv.org
The number of opioid overdose deaths has increased over the past several years, mainly
driven by an increase in the availability of highly potent synthetic opioids, like fentanyl, in the …

[HTML][HTML] Oral fentanyl consumption and withdrawal impairs fear extinction learning and enhances basolateral amygdala principal neuron excitatory-inhibitory balance …

AM Downs, G Kmiec, ZA McElligott - Addiction neuroscience, 2024 - Elsevier
The number of opioid overdose deaths has increased over the past several years, mainly
driven by an increase in the availability of highly potent synthetic opioids, like fentanyl, in the …

On the critical need to investigate the effect of alcohol in the older population.

DB Matthews, GF Koob - Alcohol, 2023 - psycnet.apa.org
This article discusses the critical need to investigate the effect of alcohol in the older
population. Perhaps one of the most critical issues facing alcohol researchers is …