Photoinduced EDA complexes enabled radical tandem cyclization/arylation of unactivated alkene with 2-Amino-1, 4-naphthoquinones

B Sun, X Shi, X Zhuang, P Huang, R Shi, R Zhu… - Organic …, 2021 - ACS Publications
A visible-light-induced radical tandem cyclization/arylation between 2-amino-1, 4-
naphthoquinone and N-allyl-2-bromo-2, 2-difluoroacetamides has been developed without …

The Different Facets of Metal‐Catalyzed C− H Functionalization Involving Quinone Compounds

JM Wood, RL de Carvalho… - The Chemical …, 2021 - Wiley Online Library
Metal‐catalysed C− H functionalization has emerged as a powerful platform for the
derivatization of quinones, a class of compounds with wide‐ranging applications. This …

Rhodium (III)-catalyzed C–H alkenylation/directing group migration for the regio-and stereoselective synthesis of tetrasubstituted alkenes

X Wu, Y Lu, J Qiao, W Dai, X Jia, H Ni, X Zhang… - Organic …, 2020 - ACS Publications
An efficient Rh (III)-catalyzed C–H alkenylation/directing group migration cascade between
indoles and alkynes for the assembly of tetrasubstituted alkenes is reported. The carbamoyl …

Ruthenium-catalyzed C–H oxygenation of quinones by weak O-coordination for potent trypanocidal agents

GG Dias, T Rogge, R Kuniyil, C Jacob… - Chemical …, 2018 - pubs.rsc.org
Ruthenium-catalysis enabled the C-5 selective C–H oxygenation of naphthoquinones, and
also sets the stage for the site-selective introduction of a hydroxyl group into …

Weakly-coordinating N-oxide and carbonyl groups for metal-catalyzed C–H activation: the case of A-ring functionalization

EN da Silva Júnior, GAM Jardim, RS Gomes… - Chemical …, 2018 - pubs.rsc.org
Compounds featuring weakly-coordinating N-oxides or carbonyl groups, as for instance,
quinoline N-oxide and quinonoid systems represent important structural scaffolds with …

Electrochemical selenation/cyclization of quinones: a rapid, green and efficient access to functionalized trypanocidal and antitumor compounds

A Kharma, C Jacob, ÍAO Bozzi… - European Journal of …, 2020 - Wiley Online Library
Electrochemical selenation in undivided electrochemical cells allows the preparation of
selenium‐containing naphthoquinones. The rapid, green and efficient protocol avoids …

Overcoming naphthoquinone deactivation: Rhodium-catalyzed C-5 selective C–H iodination as a gateway to functionalized derivatives

GAM Jardim, EN da Silva Júnior, JF Bower - Chemical Science, 2016 - pubs.rsc.org
We report a Rh-catalyzed method for the C-5 selective C–H iodination of naphthoquinones
and show that complementary C-2 selective processes can be achieved under related …

Direct sequential C–H iodination/organoyl-thiolation for the benzenoid A-ring modification of quinonoid deactivated systems: a new protocol for potent trypanocidal …

GAM Jardim, WXC Oliveira, RP de Freitas… - Organic & …, 2018 - pubs.rsc.org
We report a sequential C–H iodination/organoyl-thiolation of naphthoquinones and their
relevant trypanocidal activity. Under a combination of AgSR with a copper source, sulfur …

Regioselective C–H alkylation and alkenylation at the C5 position of 2-amino-1, 4-naphthoquinones with maleimides under Rh (iii) catalysis

PA Yakkala, D Giri, B Chaudhary, P Auti… - Organic Chemistry …, 2019 - pubs.rsc.org
Rhodium (III) catalyzed regioselective C–H alkylation and alkenylation at the C5 position of
1, 4-naphthoquinone with maleimides under acidic and basic conditions, respectively, is …

SuFEx‐Functionalized Quinones via Ruthenium‐Catalyzed C− H Alkenylation: A Potential Building Block for Bioactivity Valorization

JC de Oliveira, BU Abreu, ERS Paz… - Chemistry–An Asian …, 2024 - Wiley Online Library
Herein, we describe the Ru‐catalyzed C− H alkenylation of 1, 4‐naphthoquinones (1, 4‐
NQs), resulting in 1, 4‐naphthoquinoidal/SuFEx hybrids with moderate to good yields. This …