[HTML][HTML] Shaping the risk for late-life neurodegenerative disease: A systematic review on prenatal risk factors for Alzheimer's disease-related volumetric brain …

A Boots, AM Wiegersma, Y Vali, M van den Hof… - Neuroscience & …, 2023 - Elsevier
Environmental exposures including toxins and nutrition may hamper the developing brain in
utero, limiting the brain's reserve capacity and increasing the risk for Alzheimer's disease …

Central nervous system impact of perinatally acquired HIV in adolescents and adults: An update

SL Nichols - Current HIV/AIDS Reports, 2022 - Springer
Abstract Purpose of Review Perinatally acquired HIV infection (PHIV) can confer
neurodevelopmental risk. As children with PHIV increasingly survive through adolescence …

Early structural brain development in infants exposed to HIV and antiretroviral therapy in utero in a South African birth cohort

CJ Wedderburn, NA Groenewold, A Roos… - African Journal of …, 2022 - journals.lww.com
Introduction: There is a growing population of children who are HIV-exposed and uninfected
(HEU) with the successful expansion of antiretroviral therapy (ART) use in pregnancy …

Neurodevelopment among children exposed to HIV and uninfected in sub‐Saharan Africa

MA Bulterys, I Njuguna, M Mahy… - Journal of the …, 2023 - Wiley Online Library
Introduction The population of 16 million children exposed to HIV and uninfected (CHEU)
under 15 years of age continues to expand rapidly, and the estimated prevalence of CHEU …

[HTML][HTML] Neuroimaging young children and associations with neurocognitive development in a South African birth cohort study

CJ Wedderburn, S Subramoney, S Yeung, JP Fouche… - NeuroImage, 2020 - Elsevier
Magnetic resonance imaging (MRI) is an indispensable tool for investigating brain
development in young children and the neurobiological mechanisms underlying …

Neuroanatomical changes underlying vertical HIV infection in adolescents

X Yu, L Gao, H Wang, Z Yin, J Fang, J Chen… - Frontiers in …, 2019 - frontiersin.org
Purpose: The aim of this study was to investigate how human immunodeficiency virus (HIV)
affects brain development in adolescents, what are susceptible brain regions, and how …

Feasibility of FreeSurfer processing for T1-weighted brain images of 5-year-olds: semiautomated protocol of FinnBrain Neuroimaging Lab

EP Pulli, E Silver, V Kumpulainen… - Frontiers in …, 2022 - frontiersin.org
Pediatric neuroimaging is a quickly developing field that still faces important methodological
challenges. Pediatric images usually have more motion artifact than adult images. The …

Relationship between brain structural network integrity and emotional symptoms in youth with perinatally-acquired HIV

GA Caceres, KA Scambray, K Malee, R Smith… - Brain, Behavior, and …, 2024 - Elsevier
Perinatally acquired HIV infection (PHIV) currently affects approximately 1.7 million children
worldwide. Youth with PHIV (YPHIV) are at increased risk for emotional and behavioral …

Brain structure of perinatally HIV-infected patients on long-term treatment: A systematic review

M Van den Hof, AM Ter Haar, MWA Caan… - Neurology: Clinical …, 2019 - AAN Enterprises
Objective We aim to give an overview of the available evidence on brain structure and
function in PHIV-infected patients (PHIV+) using long-term combination antiretroviral therapy …

Initiation of antiretroviral therapy after the critical neuronal developmental period of the second postnatal year affects white matter microstructure in adolescents living …

J Hoare, SJ Heany, JP Fouche, N Phillips… - Journal of …, 2019 - Springer
Rapid maturation of major white matter pathways occurs in the first 2 years of life, indicating
a critical neuronal developmental period. The impact of initiating antiretroviral therapy (ART) …