Vectorcardiography (VCG), as an alternative to standard 12-lead electrocardiography
(ECG), represents the electrical activity of the heart. Previous studies on VCG document that …

Block of the hERG potassium channel and prolongation of the QT interval are predictors of
drug‐induced torsade de pointes. However, drugs that block the hERG potassium channel …

Vectorcardiography (VCG) is another useful method that provides us with useful spatial
information about the electrical activity of the heart. The use of vectorcardiography in clinical …

Background Congenital long QT syndrome type 2 (abnormal hERG potassium channel)
patients can develop flat, asymmetric, and notched T waves. Similar observations have been …

Fourteen drugs have been removed from the market worldwide because they cause torsade
de pointes. Most drugs that cause torsade can be identified by assessing whether they block …

Introduction Corrected QT interval (QTc) is shorter in postpubertal men than in women;
however, QTc lengthens as men age and testosterone levels decrease. Animal studies have …

Background Prolongation of the heart rate corrected QT (QTc) interval is a sensitive marker
of torsade de pointes risk; however it is not specific as QTc prolonging drugs that block …

Recently, portable electrocardiogram (ECG) hardware devices have been developed using
limb-lead measurements. However, portable ECGs provide insufficient ECG information …

Aims Increased spatial angle between QRS complex and T wave loop orientations has
repeatedly been shown to predict cardiac risk. However, there is no consensus on the …

Background Little experience exists with the heart rate correction of J-Tpeak and Tpeak-
Tend intervals. Methods In a population of 176 female and 176 male healthy subjects aged …