Botulinum neurotoxins: biology, pharmacology, and toxicology

M Pirazzini, O Rossetto, R Eleopra, C Montecucco… - Pharmacological …, 2017 - Elsevier
The study of botulinum neurotoxins (BoNT) is rapidly progressing in many aspects. Novel
BoNTs are being discovered owing to next generation sequencing, but their biologic and …

Lactose and lactose-derived oligosaccharides: More than prebiotics?

XY Chen, MG Gänzle - International Dairy Journal, 2017 - Elsevier
Valorization of lactose is achieved by enzymatic conversion to lactose derivatives with
nutraceutical properties. This review summarizes recent developments on composition and …

The long journey of botulinum neurotoxins into the synapse

A Rummel - Toxicon, 2015 - Elsevier
Botulinum neurotoxins (BoNT) cause the disease botulism, a flaccid paralysis of the muscle.
They are also very effective, widely used medicines applied locally in sub-nanogram …

Generation and characterization of six recombinant botulinum neurotoxins as reference material to serve in an international proficiency test

J Weisemann, N Krez, U Fiebig, S Worbs, M Skiba… - Toxins, 2015 - mdpi.com
The detection and identification of botulinum neurotoxins (BoNT) is complex due to the
existence of seven serotypes, derived mosaic toxins and more than 40 subtypes. Expert …

Dietary, nondigestible oligosaccharides and Bifidobacterium breve M-16V suppress allergic inflammation in intestine via targeting dendritic cell maturation

S de Kivit, AI Kostadinova, JA Kerperien… - Journal of Leukocyte …, 2017 - academic.oup.com
Dietary intervention with short-chain galacto-oligosaccharides (scGOS), long-chain fructo-
oligosaccharides (lcFOS) and Bifidobacterium breve M-16V (Bb)(GF/Bb) suppresses food …

The cryo‐EM structure of the BoNT/Wo‐NTNH complex reveals two immunoglobulin‐like domains

S Košenina, J Škerlová, S Zhang, M Dong… - The FEBS …, 2024 - Wiley Online Library
The botulinum neurotoxin‐like toxin from Weissella oryzae (BoNT/Wo) is one of the BoNT‐
like toxins recently identified outside of the Clostridium genus. We show that, like the …

The hypothetical protein P47 of Clostridium botulinum E1 strain Beluga has a structural topology similar to bactericidal/permeability-increasing protein

K Lam, R Qi, S Liu, A Kroh, G Yao, K Perry, A Rummel… - Toxicon, 2018 - Elsevier
Botulinum neurotoxins (BoNTs) are causative agents of the life-threatening disease
botulism. They are naturally produced by species of the bacteria Clostridium botulinum as …

Botulinum neurotoxin, tetanus toxin, and anthrax lethal factor countermeasures

EA Ambrose - Zinc Enzyme Inhibitors: Enzymes from Microorganisms, 2017 - Springer
Bioterrorism constitutes the deliberate release and dissemination of biological agents to
incapacitate, maim, or kill individuals, groups, or populations, including humans, animals …

 Structure and Function Relationships of Exopolysaccharides Produced by Lactic Acid Bacteria

X Chen - 2017 - era.library.ualberta.ca
Lactic acid bacteria produce glycans that may be applied in food and pharmaceutical
industries as prebiotics, food additives, to prevent pathogen adhesion, or to modulate the …

[HTML][HTML] Faltenkiller gegen Schmerzen

F gegen Schmerzen - deutsche-apotheker-zeitung.de
Das grampositive, sporenbildende anaerobe Bakterium Clostridium botulinum produziert
Neurotoxine, von denen bisher acht Subtypen (A, B, C1, D, E, F, G und H) bekannt sind …