Neurotoxicity in acute and repeated organophosphate exposure

SX Naughton, AV Terry Jr - Toxicology, 2018 - Elsevier
The term organophosphate (OP) refers to a diverse group of chemicals that are found in
hundreds of products worldwide. As pesticides, their most common use, OPs are clearly …

Organophosphate toxicity: Updates of malathion potential toxic effects in mammals and potential treatments

AM Badr - Environmental science and pollution research, 2020 - Springer
Organophosphorus insecticides toxicity is still considered a major global health problem.
Malathion is one of the most commonly used organophosphates nowadays, as being …

Health consequences of exposure to aircraft contaminated air and fume events: a narrative review and medical protocol for the investigation of exposed aircrew and …

J Burdon, LT Budnik, X Baur, G Hageman… - Environmental …, 2023 - Springer
Thermally degraded engine oil and hydraulic fluid fumes contaminating aircraft cabin air
conditioning systems have been well documented since the 1950s. Whilst …

Alpha-synuclein in peripheral tissues as a possible marker for neurological diseases and other medical conditions

FJ Jiménez-Jiménez, H Alonso-Navarro… - Biomolecules, 2023 - mdpi.com
The possible usefulness of alpha-synuclein (aSyn) determinations in peripheral tissues
(blood cells, salivary gland biopsies, olfactory mucosa, digestive tract, skin) and in biological …

Elevated serum α-synuclein autoantibodies in patients with parkinson's disease relative to Alzheimer's disease and controls

A Shalash, M Salama, M Makar, T Roushdy… - Frontiers in …, 2017 - frontiersin.org
Early diagnosis of neurodegenerative diseases is of paramount importance for successful
treatment. Lack of sensitive and early biomarkers for diagnosis of diseases like Parkinson's …

[HTML][HTML] S100 proteins: Diagnostic and prognostic biomarkers in laboratory medicine

CW Heizmann - Biochimica et Biophysica Acta (BBA)-Molecular Cell …, 2019 - Elsevier
S100 proteins are members of the superfamily of Ca 2+-binding proteins characterized by
the specific Ca 2+-binding motif, the EF-hand. Proteins of this superfamily are of clinical use …

Bisphenol-A exposure induced neurotoxicity and associated with synapse and cytoskeleton in Neuro-2a cells

Z Yin, L Hua, L Chen, D Hu, J Li, Z An, T Tian, H Ning… - Toxicology in Vitro, 2020 - Elsevier
Bisphenol A (BPA) is an environmental chemical that induces neurotoxic effects for human.
Synaptophysin (SYP) and drebrin (Dbn) proteins are involved in regulating synaptic …

The innate immune system and inflammatory priming: potential mechanistic factors in mood disorders and Gulf War illness

KJ Trageser, M Sebastian-Valverde… - Frontiers in …, 2020 - frontiersin.org
Gulf War Illness is a chronic multisystem disorder affecting approximately a third of the
Veterans of the Gulf War, manifesting with physical and mental health symptoms such as …

Effects of endocrine disrupting chemicals on myelin development and diseases

V Naffaa, O Laprévote, AL Schang - Neurotoxicology, 2021 - Elsevier
In the central and peripheral nervous systems, myelin is essential for efficient conduction of
action potentials. During development, oligodendrocytes and Schwann cells differentiate …

Repeated exposures to diisopropylfluorophosphate result in structural disruptions of myelinated axons and persistent impairments of axonal transport in the brains of …

SX Naughton, CM Hernandez, WD Beck, I Poddar… - Toxicology, 2018 - Elsevier
Organophosphates (OPs) are found in hundreds of valuable agricultural, industrial, and
commercial compounds; however, they have also been associated with a variety of harmful …