Electrospinning is a unique technique, which provides forming of polymeric scaffolds for soft
tissue engineering, which include tissue scaffolds for soft tissues of the cardiovascular …

The development of intimal hyperplasia (IH) near the anastomosis of a vascular graft to
artery is directly related to changes in the wall shear rate distribution. Mismatch in …

All anastomotic intimal thickening may not be the same, and the underlying mechanism (s)
regulating the different types may vary. We investigated the localization of experimental …

Despite much effort, synthetic small diameter vascular grafts still face limited success due to
vascular wall thickening known as intimal hyperplasia (IH). Compliance mismatch between …

Failure of long-term synthetic arterial bypass grafts has been attributed in part to anastomotic
stenosis, but the pathologic basis for this has not been determined. Which cells participate in …

In order to analyse the wall mechanics and the flow dynamics in compliant vascular distal
end-to-side anastomoses, computer simulation has been performed. In a model study the …

The development and progress of distal anastomotic intimal hyperplasia seems to be
promoted by altered flow conditions and intramural stress distributions at the region of the …

Unusual wall shear stress patterns on the bed of end-to-side arterial anastomoses appear to
be the primary factor in the development of intimal hyperplasia that often leads to arterial …

Abstract Endothelin-1, a 21-amino acid peptide secreted by endothelial cells, has constrictor
and mitogenic activity for vascular smooth muscle cells, and its mitogenic activity is …

The observation of intimal hyperplasia at bypass graft anastomoses has suggested a
potential interaction between local hemodynamics and vascular wall response. Wall shear …