Methodological approaches, challenges, and opportunities in the application of Mendelian randomisation to lifecourse epidemiology: A systematic literature review
Diseases diagnosed in adulthood may have antecedents throughout (including prenatal)
life. Gaining a better understanding of how exposures at different stages in the lifecourse …
life. Gaining a better understanding of how exposures at different stages in the lifecourse …
[HTML][HTML] Review of mendelian randomization studies on age at natural menopause
X Zhang, Z Huangfu, S Wang - Frontiers in Endocrinology, 2023 - frontiersin.org
Menopause marks the end of the reproductive phase of life. Based on epidemiological
studies, abnormal age at natural menopause (ANM) is thought to contribute to a number of …
studies, abnormal age at natural menopause (ANM) is thought to contribute to a number of …
[HTML][HTML] Evaluation of bi-directional causal association between obstructive sleep apnoea syndrome and diabetic microangiopathy: a Mendelian randomization study
Q Liu, X Chang, R Lian, Q Chen, J Wang… - Frontiers in …, 2024 - ncbi.nlm.nih.gov
Objective This study aimed to use bidirectional two-sample Mendelian Randomization (MR)
to assess the causal relationship between OSAS and diabetic microangiopathy. Methods …
to assess the causal relationship between OSAS and diabetic microangiopathy. Methods …
Maternal origin of children-onset asthma: evidence from observational study and instrumental variable analysis
S Jin, Y Wu, S Zhang, T Gao, Y Liu, Z Ping, T Wang - 2023 - researchsquare.com
Background An inverse association was observed between birthweight and children-onset
asthma (COA), the origin of the connection however remains elusive. Instrumental variable …
asthma (COA), the origin of the connection however remains elusive. Instrumental variable …
Genetic Overlap and Instrumental Causal Inference Using Polygenetic Risk Score to Assess the Relationship between Birthweight and Children-Onset Asthma
S Jin, Y Wu, T Gao, Y Liu, F Guan, T Wang… - Available at SSRN … - papers.ssrn.com
Background: An inverse association was observed between birthweight and children-onset
asthma (COA), the origin of such connection however remains elusive. Genetic analysis …
asthma (COA), the origin of such connection however remains elusive. Genetic analysis …