Abstract The World Health Organization (WHO) has declared coronavirus disease 2019
(COVID-19), the disease caused by the severe acute respiratory syndrome coronavirus 2 …

Background Severe trauma continues to represent a global public health issue and mortality
and morbidity in trauma patients remains substantial. A number of initiatives have aimed to …

Bleeding remains the leading cause of preventable death following injury1. Contributing to
this problem, coagulopathy develops in approximately one-third of all injured patients2-4 …

Now in its sixth edition, Robert M. Bojar's Manual of Perioperative Care in Adult Cardiac
Surgery remains the go-to practical guide for all of those involved in the care of the cardiac …

Background Trauma-induced coagulopathy (TIC) is common in trauma patients with major
hemorrhage. Prothrombin complex concentrate (PCC) is used as a potential treatment for …

A comprehensive understanding of thrombus formation as a physicochemical process that
has evolved to protect the integrity of the human vasculature is critical to our ability to predict …

Background Perioperative bleeding and transfusion are important causes of morbidity and
mortality in patients undergoing liver transplantation. The aim of this study is to assess …

Developed for the International Association for Trauma Surgery and Intensive Care (IATSIC),
the Manual of Definitive Surgical Trauma Care 5e is ideal for training all surgeons who …

Resuscitation of the critically ill patient with fluid and blood products is one of the most
widespread interventions in medicine. This is especially relevant for trauma patients, as …

Massive transfusion protocols (MTPs) are established to provide rapid blood replacement in
a setting of severe hemorrhage. Early optimal blood transfusion is essential to sustain organ …