Environmental influences on the epigenome: exposure-associated DNA methylation in human populations

EM Martin, RC Fry - Annual review of public health, 2018 - annualreviews.org
DNA methylation is the most well studied of the epigenetic regulators in relation to
environmental exposures. To date, numerous studies have detailed the manner by which …

Sex-specific neurotoxic effects of heavy metal pollutants: Epidemiological, experimental evidence and candidate mechanisms

M Gade, N Comfort, DB Re - Environmental research, 2021 - Elsevier
The heavy metals lead (Pb), mercury (Hg), and cadmium (Cd) are ubiquitous environmental
pollutants and are known to exert severe adverse impacts on the nervous system even at …

The environment and male reproduction: The effect of cadmium exposure on reproductive function and its implication in fertility

C De Angelis, M Galdiero, C Pivonello, C Salzano… - Reproductive …, 2017 - Elsevier
Cadmium is an environmental pollutant known as endocrine disruptor. Testis is particularly
susceptible to cadmium, and testis injury occurs at high but even low levels of exposure …

[HTML][HTML] Before the beginning: environmental exposures and reproductive and obstetrical outcomes

TR Segal, LC Giudice - Fertility and sterility, 2019 - Elsevier
There is growing consensus that preconception exposure to environmental toxins can
adversely affect fertility, pregnancy, and fetal development, which may persist into the …

Small-magnitude effect sizes in epigenetic end points are important in children's environmental health studies: the children's environmental health and disease …

CV Breton, CJ Marsit, E Faustman… - Environmental …, 2017 - ehp.niehs.nih.gov
Background: Characterization of the epigenome is a primary interest for children's
environmental health researchers studying the environmental influences on human …

Cadmium: Toxic effects on placental and embryonic development

HX Geng, L Wang - Environmental toxicology and pharmacology, 2019 - Elsevier
Cadmium is a non-essential trace metal that has strong teratogenic and mutagenic effects in
living organisms. The content is more highly enriched in women than in men and can enter …

Sex-dependent effects of cadmium exposure in early life on gut microbiota and fat accumulation in mice

Q Ba, M Li, P Chen, C Huang, X Duan… - Environmental …, 2017 - ehp.niehs.nih.gov
Background: Environmental cadmium, with a high average dietary intake, is a severe public
health risk. However, the long-term health implications of environmental exposure to …

Environmental chemicals and DNA methylation in adults: a systematic review of the epidemiologic evidence

A Ruiz-Hernandez, CC Kuo, P Rentero-Garrido… - Clinical …, 2015 - Springer
Current evidence supports the notion that environmental exposures are associated with
DNA-methylation and expression changes that can impact human health. Our objective was …

[HTML][HTML] Effects of environmental exposures on fetal and childhood growth trajectories

T Zheng, J Zhang, K Sommer, BA Bassig, X Zhang… - Annals of global …, 2016 - Elsevier
Delayed fetal growth and adverse birth outcomes are some of the greatest public health
threats to this generation of children worldwide because these conditions are major …

Praegnatio perturbatio—impact of endocrine-disrupting chemicals

V Padmanabhan, W Song… - Endocrine …, 2021 - academic.oup.com
The burden of adverse pregnancy outcomes such as preterm birth and low birth weight is
considerable across the world. Several risk factors for adverse pregnancy outcomes have …