Respiratory syncytial virus infection and novel interventions

AC Langedijk, LJ Bont - Nature Reviews Microbiology, 2023 - nature.com
The large global burden of respiratory syncytial virus (RSV) respiratory tract infections in
young children and older adults has gained increased recognition in recent years. Recent …

Respiratory syncytial virus: infection, detection, and new options for prevention and treatment

C Griffiths, SJ Drews, DJ Marchant - Clinical microbiology reviews, 2017 - Am Soc Microbiol
Respiratory syncytial virus (RSV) infection is a significant cause of hospitalization of children
in North America and one of the leading causes of death of infants less than 1 year of age …

Decline in pneumococcal disease in young children during the coronavirus disease 2019 (COVID-19) pandemic in Israel associated with suppression of seasonal …

D Danino, S Ben-Shimol… - Clinical Infectious …, 2022 - academic.oup.com
Background The incidence of invasive pneumococcal disease (IPD) declined during the
COVID-19 pandemic. Previous studies hypothesized that this was due to reduced …

Nasopharyngeal microbiota, host transcriptome, and disease severity in children with respiratory syncytial virus infection

WAA de Steenhuijsen Piters, S Heinonen… - American journal of …, 2016 - atsjournals.org
Rationale: Respiratory syncytial virus (RSV) is the leading cause of acute lower respiratory
tract infections and hospitalizations in infants worldwide. Known risk factors, however …

[HTML][HTML] Integrated omics endotyping of infants with respiratory syncytial virus bronchiolitis and risk of childhood asthma

Y Raita, M Pérez-Losada, RJ Freishtat… - Nature …, 2021 - nature.com
Respiratory syncytial virus (RSV) bronchiolitis is not only the leading cause of hospitalization
in US infants, but also a major risk factor for asthma development. While emerging evidence …

Direct interactions with influenza promote bacterial adherence during respiratory infections

HM Rowe, VA Meliopoulos, A Iverson, P Bomme… - Nature …, 2019 - nature.com
Epidemiological observations and animal models have long shown synergy between
influenza virus infections and bacterial infections. Influenza virus infection leads to an …

[HTML][HTML] Virus interactions with bacteria: Partners in the infectious dance

U Neu, BA Mainou - PLoS Pathogens, 2020 - journals.plos.org
The outcome of viral infection depends on the interplay between host factors and the
environment. Host factors, like the expression of viral receptors, convey permissiveness to …

[HTML][HTML] Outcomes of respiratory viral-bacterial co-infection in adult hospitalized patients

Y Liu, L Ling, SH Wong, MHT Wang, JR Fitzgerald… - …, 2021 - thelancet.com
Background Viral infections of the respiratory tract represent a major global health concern.
Co-infection with bacteria may contribute to severe disease and increased mortality in …

Respiratory viral sepsis: epidemiology, pathophysiology, diagnosis and treatment

X Gu, F Zhou, Y Wang, G Fan… - European Respiratory …, 2020 - Eur Respiratory Soc
According to the Third International Consensus Definition for Sepsis and Septic Shock,
sepsis is a life-threatening organ dysfunction resulting from dysregulated host responses to …

[HTML][HTML] Viral-bacterial coinfection affects the presentation and alters the prognosis of severe community-acquired pneumonia

G Voiriot, B Visseaux, J Cohen, LBL Nguyen… - Critical Care, 2016 - Springer
Background Multiplex polymerase chain reaction (mPCR) enables recovery of viruses from
airways of patients with community-acquired pneumonia (CAP), although their clinical …