The microbiome–gut–brain axis in Parkinson disease—from basic research to the clinic

AH Tan, SY Lim, AE Lang - Nature Reviews Neurology, 2022 - nature.com
Evidence for a close bidirectional link between the brain and the gut has led to a paradigm
shift in neurology, especially in the case of Parkinson disease (PD), in which gastrointestinal …

Mediterranean diet and health: A systematic review of epidemiological studies and intervention trials

ML Sánchez-Sánchez, A García-Vigara… - Maturitas, 2020 - Elsevier
Diet is a crucial variable for a healthy life. A rapidly growing number of studies in recent
years support the hypothesis that the Mediterranean diet (MedDiet) has a beneficial effect on …

Association of fecal and plasma levels of short-chain fatty acids with gut microbiota and clinical severity in patients with Parkinson disease

SJ Chen, CC Chen, HY Liao, YT Lin, YW Wu, JM Liou… - Neurology, 2022 - AAN Enterprises
Background and Objectives Short-chain fatty acids (SCFAs) are gut microbial metabolites
that promote the disease process in a rodent model of Parkinson disease (PD), but fecal …

Mediterranean diet adherence is related to reduced probability of prodromal Parkinson's disease

MI Maraki, M Yannakoulia, M Stamelou… - Movement …, 2019 - Wiley Online Library
ABSTRACT Background The International Parkinson and Movement Disorder Society
recently introduced a methodology for probability score calculation for prodromal PD …

Diet in Parkinson's disease: critical role for the microbiome

A Jackson, CB Forsyth, M Shaikh, RM Voigt… - Frontiers in …, 2019 - frontiersin.org
Background: Parkinson's disease (PD) is the most common movement disorder affecting up
to 1% of the population above the age of 60 and 4–5% of those above the age of 85. Little …

[HTML][HTML] The gut-brain vascular axis in neuroinflammation

S Carloni, M Rescigno - Seminars in immunology, 2023 - Elsevier
The multifaceted microbiota characterizing our gut plays a crucial role in maintaining
immune, metabolic and tissue homeostasis of the intestine as well as of distal organs …

The role of diet and dietary patterns in Parkinson's disease

E Knight, T Geetha, D Burnett, JR Babu - Nutrients, 2022 - mdpi.com
Parkinson's Disease (PD) is a neurodegenerative disorder associated with diminished
nutrition status and decreased quality of life. While the prevalence of PD is expected to …

Stool immune profiles evince gastrointestinal inflammation in Parkinson's disease

MC Houser, J Chang, SA Factor, ES Molho… - Movement …, 2018 - Wiley Online Library
Background: Gastrointestinal symptoms are common in Parkinson's disease and frequently
precede the development of motor impairments. Intestinal inflammation has been proposed …

Diet pattern and prodromal features of Parkinson disease

S Molsberry, K Bjornevik, KC Hughes, B Healy… - Neurology, 2020 - AAN Enterprises
Objective To assess the relationship between diet pattern and prodromal Parkinson disease
(PD) features. Methods These analyses include 47,679 participants from the Nurses' Health …

The gut microbiome in Parkinson's disease: A culprit or a bystander?

A Keshavarzian, P Engen, S Bonvegna… - Progress in brain research, 2020 - Elsevier
In recent years, large-scale metagenomics projects such as the Human Microbiome Project
placed the gut microbiota under the spotlight of research on its role in health and in the …