Single-neuron analysis of dendrites and axons reveals the network organization in mouse prefrontal cortex
The structures of dendrites and axons form the basis for the connectivity of neural network,
but their precise relationship at single-neuron level remains unclear. Here we report the …
but their precise relationship at single-neuron level remains unclear. Here we report the …
From Analog to Digital Computing: Is Homo sapiens' Brain on Its Way to Become a Turing Machine?
The abstract basis of modern computation is the formal description of a finite state machine,
the Universal Turing Machine, based on manipulation of integers and logic symbols. In this …
the Universal Turing Machine, based on manipulation of integers and logic symbols. In this …
CARLsim 6: an open source library for large-scale, biologically detailed spiking neural network simulation
Mature simulation systems for Spiking Neural Networks (SNNs) become more relevant than
ever for understanding the brain and supporting neuromorphic computing. The CARL-sim …
ever for understanding the brain and supporting neuromorphic computing. The CARL-sim …
Hippocampome. org 2.0 is a knowledge base enabling data-driven spiking neural network simulations of rodent hippocampal circuits
Hippocampome. org is a mature open-access knowledge base of the rodent hippocampal
formation focusing on neuron types and their properties. Previously, Hippocampome. org v1 …
formation focusing on neuron types and their properties. Previously, Hippocampome. org v1 …
An update to Hippocampome. org by integrating single-cell phenotypes with circuit function in vivo
A Sanchez-Aguilera, DW Wheeler, T Jurado-Parras… - PLoS …, 2021 - journals.plos.org
Understanding brain operation demands linking basic behavioral traits to cell-type specific
dynamics of different brain-wide subcircuits. This requires a system to classify the basic …
dynamics of different brain-wide subcircuits. This requires a system to classify the basic …
Prenatal PM2.5 exposure impairs spatial learning and memory in male mice offspring: from transcriptional regulation to neuronal morphogenesis
Y Hou, W Yan, L Guo, G Li, N Sang - Particle and Fibre Toxicology, 2023 - Springer
Background As one of the environmental risk factors for human health, atmospheric fine
particulate matter (PM2. 5) contributes to cognitive deterioration in addition to respiratory …
particulate matter (PM2. 5) contributes to cognitive deterioration in addition to respiratory …
Multiscale modeling of neuronal dynamics in hippocampus CA1
The development of biologically realistic models of brain microcircuits and regions
constitutes currently a very relevant topic in computational neuroscience. One of the main …
constitutes currently a very relevant topic in computational neuroscience. One of the main …
Full-scale scaffold model of the human hippocampus CA1 area
D Gandolfi, J Mapelli, SMG Solinas… - Nature Computational …, 2023 - nature.com
The increasing availability of quantitative data on the human brain is opening new avenues
to study neural function and dysfunction, thus bringing us closer and closer to the …
to study neural function and dysfunction, thus bringing us closer and closer to the …
Robust resting-state dynamics in a large-scale spiking neural network model of area CA3 in the mouse hippocampus
Hippocampal area CA3 performs the critical auto-associative function underlying pattern
completion in episodic memory. Without external inputs, the electrical activity of this neural …
completion in episodic memory. Without external inputs, the electrical activity of this neural …
A realistic morpho-anatomical connection strategy for modelling full-scale point-neuron microcircuits
D Gandolfi, J Mapelli, S Solinas, R De Schepper… - Scientific Reports, 2022 - nature.com
The modeling of extended microcircuits is emerging as an effective tool to simulate the
neurophysiological correlates of brain activity and to investigate brain dysfunctions …
neurophysiological correlates of brain activity and to investigate brain dysfunctions …