2015 American College of Rheumatology guideline for the treatment of rheumatoid arthritis

JA Singh, KG Saag, SL Bridges Jr, EA Akl… - Arthritis & …, 2016 - Wiley Online Library
Objective To develop a new evidence‐based, pharmacologic treatment guideline for
rheumatoid arthritis (RA). Methods We conducted systematic reviews to synthesize the …

Mechanism of action of methotrexate in rheumatoid arthritis, and the search for biomarkers

PM Brown, AG Pratt, JD Isaacs - Nature Reviews Rheumatology, 2016 - nature.com
The treatment and outcomes of patients with rheumatoid arthritis (RA) have been
transformed over the past two decades. Low disease activity and remission are now …

EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2013 update

JS Smolen, R Landewé, FC Breedveld… - Annals of the …, 2014 - ard.bmj.com
In this article, the 2010 European League against Rheumatism (EULAR) recommendations
for the management of rheumatoid arthritis (RA) with synthetic and biological disease …

Efficacy, duration of use and safety of glucocorticoids: a systematic literature review informing the 2022 update of the EULAR recommendations for the management of …

SA Bergstra, A Sepriano, A Kerschbaumer… - Annals of the …, 2023 - ard.bmj.com
This systematic literature review (SLR) regarding the efficacy, duration of use and safety of
glucocorticoids (GCs), was performed to inform the 2022 update of the EULAR …

Methotrexate monotherapy and methotrexate combination therapy with traditional and biologic disease modifying anti‐rheumatic drugs for rheumatoid arthritis: a …

GS Hazlewood, C Barnabe… - Cochrane Database …, 2016 - cochranelibrary.com
Background Methotrexate is considered the preferred disease‐modifying anti‐rheumatic
drug (DMARD) for the treatment of rheumatoid arthritis, but controversy exists on the …

2018 update of the APLAR recommendations for treatment of rheumatoid arthritis

CS Lau, F Chia, L Dans, A Harrison… - … journal of rheumatic …, 2019 - Wiley Online Library
Aim To update recommendations based on current best evidence concerning the treatment
of rheumatoid arthritis (RA), focusing particularly on the role of targeted therapies, to inform …

Efficacy and safety of low-dose interleukin-2 in combination with methotrexate in patients with active rheumatoid arthritis: a randomized, double-blind, placebo …

X Zhang, M Miao, R Zhang, X Liu, X Zhao… - … and Targeted Therapy, 2022 - nature.com
Rheumatoid arthritis (RA) is an aggressive autoimmune arthritis, and current therapies
remain unsatisfactory due to low remission rate and substantially adverse effects. Low-dose …

Time trends in disease activity, response and remission rates in rheumatoid arthritis during the past decade: results from the NOR-DMARD study 2000–2010

AB Aga, E Lie, T Uhlig, IC Olsen, A Wierød… - Annals of the …, 2015 - ard.bmj.com
Objectives To investigate whether baseline disease activity levels and responses in patients
with rheumatoid arthritis (RA) changed during the period 2000–2010. Methods Data were …

Efficacy of glucocorticoids, conventional and targeted synthetic disease-modifying antirheumatic drugs: a systematic literature review informing the 2016 update of the …

K Chatzidionysiou, S Emamikia, J Nam… - Annals of the …, 2017 - ard.bmj.com
Objectives To perform a systematic literature review (SLR) informing the 2016 update of the
recommendations for the management of rheumatoid arthritis (RA). Methods An SLR for the …

Remission induction comparing infliximab and high-dose intravenous steroid, followed by treat-to-target: a double-blind, randomised, controlled trial in new-onset …

JL Nam, E Villeneuve, EMA Hensor… - Annals of the …, 2014 - ard.bmj.com
Objectives In disease modifying antirheumatic drug (DMARD)-naive early rheumatoid
arthritis (RA), to compare the efficacy of methotrexate (MTX) and infliximab (IFX) with MTX …