The blood-brain barrier (BBB), constituted by an extensive network of endothelial cells (ECs)
together with neurons and glial cells, including microglia, forms the neurovascular unit …

In recent years neurodevelopmental problems in children have increased at a rate that
suggests lifestyle factors and chemical exposures as likely contributors. When …

Multiple sclerosis (MS) is widely considered to be the result of an aggressive autoreactive T
cell attack on myelin. How these autoimmune responses arise in MS is unclear, but they …

Schizophrenia is a chronic and debilitating mental illness characterized by a broad range of
abnormal behaviors, including delusions and hallucinations, impaired cognitive function, as …

Minocycline is a second-generation, semi-synthetic tetracycline that has been in use in
therapy for over 30 years for its antibiotic properties against both Gram-positive and Gram …

Although the primary cause of multiple sclerosis (MS) is unknown, the widely accepted view
is that aberrant (auto) immune responses possibly arising following infection (s) are …

To review the neuroprotective effects of minocycline in focal cerebral ischemia in animal
models. By searching in the databases of PubMed, ScienceDirect, and Scopus, and …

Multiple sclerosis (MS) is a progressive inflammatory and demyelinating disease that affects
more than 2.5 million people worldwide every year. Current therapies use mostly disease …

Spinal cord injury can have a range of debilitating effects, permanently impacting a patient's
quality of life. Initially thought to be an immune privileged site, the spinal cord is able to …

Psychiatric disorders have long and dominantly been regarded to be induced by
disturbances of neuronal networks including synapses and neurotransmitters. Thus, the …