Natural bioactive compounds useful in clinical management of metabolic syndrome

A Noce, M Di Lauro, F Di Daniele… - Nutrients, 2021 - mdpi.com
Metabolic syndrome (MetS) is a clinical manifestation characterized by a plethora of
comorbidities, including hyperglycemia, abdominal obesity, arterial hypertension, and …

Therapeutic properties and use of extra virgin olive oil in clinical nutrition: A narrative review and literature update

A Jiménez-Sánchez, AJ Martínez-Ortega… - Nutrients, 2022 - mdpi.com
Extra virgin olive oil (EVOO) is a cornerstone of the Mediterranean diet (MedD). In this
narrative review, we synthesize and illustrate the various characteristics and clinical …

Metabolism and bioavailability of olive bioactive constituents based on in vitro, in vivo and human studies

T Nikou, ME Sakavitsi, E Kalampokis, M Halabalaki - Nutrients, 2022 - mdpi.com
Consumption of olive products has been established as a health-promoting dietary pattern
due to their high content in compounds with eminent pharmacological properties and well …

Oral bioavailability and metabolism of hydroxytyrosol from food supplements

C Bender, S Strassmann, C Golz - Nutrients, 2023 - mdpi.com
Table olives and olive oils are the main dietary sources of hydroxytyrosol (HT), a natural
antioxidant compound that has emerged as a potential aid in protection against …

Absorption, distribution, metabolism, and excretion of the main olive tree phenols and polyphenols: A literature review

S Galmés, B Reynés, M Palou… - Journal of Agricultural …, 2021 - ACS Publications
The effects of olive tree (poly) phenols (OPs) are largely dependent upon their bioavailability
and metabolization by humans. Absorption, distribution, metabolism, and excretion (ADME) …

From the gut to the brain: the long journey of phenolic compounds with neurocognitive effects

I Domínguez-López, A López-Yerena… - Nutrition …, 2025 - academic.oup.com
The human gut microbiota is a complex community of micro-organisms that play a crucial
role in maintaining overall health. Recent research has shown that gut microbes also have a …

Anti-inflammatory effects of nutritionally relevant concentrations of oleuropein and hydroxytyrosol on peripheral blood mononuclear cells: an age-related analysis

F Pojero, F Gervasi, SD Fiore, A Aiello… - International Journal of …, 2023 - mdpi.com
Immunosenescence and inflammaging facilitate the insurgence of chronic diseases. The
Mediterranean diet is a non-invasive intervention to improve the chronic low-grade …

Phenylboronic acid-grafted chitosan nanocapsules for effective delivery and controllable release of natural antioxidants: Olive oil and hydroxytyrosol

OM Hendawy, MM Al-Sanea, RM Elbargisy… - Pharmaceutics, 2022 - mdpi.com
Olives and virgin olive oil (VOO) are a staple of Mediterranean diets and are rich in several
beneficial phenolic compounds, including hydroxytyrosol (HT). Therefore, VOO was …

Potential of olive oil and its phenolic compounds as therapeutic intervention against colorectal cancer: a comprehensive review

A Sain, S Sahu, D Naskar - British Journal of Nutrition, 2022 - cambridge.org
Colorectal cancer (CRC) is one of the major causes of death across the world and incidence
rate of CRC increasing alarmingly each passing year. Diet, genomic anomalies …

[HTML][HTML] Modulation of biomarkers associated with risk of cancer in humans by olive oil intake: A systematic review

HR Pessoa, L Zago, CC Curioni… - Journal of Functional …, 2022 - Elsevier
This systematic review summarized the role of olive oil intake in modulation of cancer risk
biomarkers in healthy adults. A total of four randomized clinical trials with crossover design …