Acute kidney injury (AKI) and chronic kidney disease (CKD) are global health burdens with
rising prevalence. Their bidirectional relationship with cardiovascular dysfunction …

The modification of nuclear, cytoplasmic, and mitochondrial proteins by O-linked β-N-
acetylglucosamine (O-GlcNAc) is an essential post-translational modification common in …

Modelling human diseases serves as a crucial tool to unveil underlying mechanisms and
pathophysiology. Takotsubo syndrome (TS), an acute form of heart failure resembling …

Stress cardiomyopathy (SCM) is associated with cardiovascular mortality rates similar to
acute coronary syndrome. Myocardial injuries driven by inflammatory mechanisms may in …

Mitral regurgitation (MR) is associated with morphological and functional alterations of left
atrium (LA) and ventricle (LV), possibly inducing LA–LV misalignment. We aimed to:(1) …

The pyrimidine nucleoside uridine and its phosphorylated derivates have been shown to be
involved in the systemic regulation of energy and redox balance and promote the …

Acute Stress Disorder (ASD) is a psychiatric condition that can develop shortly after trauma
exposure. Although molecular studies of ASD are only beginning, groups of metabolites …

Cardiac fibrosis is a major and complex pathophysiological process that ultimately
culminates in cardiac dysfunction and heart failure. This phenomenon includes not only the …

Background Myocardial infarction (MI) is a serious heart ailment that requires cutting-edge
remedies for effective treatment. This study examines the possible cardioprotective effects of …

Aims Adequate animal models are necessary to understand human conditions, such as
takotsubo syndrome (TS) characterized by the heart's transient regional wall motion …