The bone marrow is responsible for producing an incredible number of cells daily in order to
maintain blood homeostasis through a process called hematopoiesis. Hematopoiesis is a …

Abstract Background Recently, FAM83H was reported to have roles in cancer progression in
conjunction with oncogenic molecules such as MYC and b-catenin. Moreover, the data from …

Background Expansion of multi-C2H2 domain zinc finger (ZNF) genes, including the
Krüppel-associated box (KRAB) subfamily, paralleled the evolution of tetrapodes …

Genome-wide association study (GWAS) have identified a large number of SNPs associated
with milk production traits in dairy cattle. Behind SNPs, INDELs are the second most …

Abstract Background The COP9/signalosome (CSN) is a highly conserved eight subunit
complex that, by deneddylating cullins in cullin-based E3 ubiquitin ligases, regulates protein …

Zinc as an essential element plays the crucial role in many physiological, but also
pathological processes-zinc controls cell proliferation, differentiation, and viability including …

Previously, we characterized a zinc finger protein gene HZF1 (ZNF16) and demonstrated
that it played a significant role in the erythroid and megakaryocytic differentiation of K562 …

Zinc finger proteins have been implicated as transcription factors in the differentiation and
development of cells and tissues in higher organisms. The classical C2H2 zinc finger motif is …

Purpose Proteins in the vitreous play an important role on the induction of proliferative
vitreoretinopathy (PVR) after retinal detachment. The aim of this study was to investigate the …

Alternative splicing is a pervasive mechanism of RNA maturation in higher eukaryotes,
which increases proteomic diversity and biological complexity. It has a key regulatory role in …