[HTML][HTML] Exploring LIPIDs for their potential to improves bioavailability of lipophilic drugs candidates: A review

S Sambhakar, R Saharan, S Narwal, R Malik… - Saudi Pharmaceutical …, 2023 - Elsevier
This review aims to provide a thorough examination of the benefits, challenges, and
advancements in utilizing lipids for more effective drug delivery, ultimately contributing to the …

Lipid–an emerging platform for oral delivery of drugs with poor bioavailability

S Chakraborty, D Shukla, B Mishra, S Singh - European journal of …, 2009 - Elsevier
The sole objective of pharmaceutical science is to design successful dosage forms which
fulfill the therapeutic needs of the patients effectively. Development of new drug entities is …

Effects of intraduodenal fatty acids on appetite, antropyloroduodenal motility, and plasma CCK and GLP-1 in humans vary with their chain length

KL Feltrin, TJ Little, JH Meyer… - American Journal …, 2004 - journals.physiology.org
The gastrointestinal effects of intraluminal fats may be critically dependent on the chain
length of fatty acids released during lipolysis. We postulated that intraduodenal …

Gastrointestinal targets of appetite regulation in humans

N Delzenne, J Blundell, F Brouns… - Obesity …, 2010 - Wiley Online Library
The aim of this paper is to describe and discuss relevant aspects of the assessment of
physiological functions–and related biomarkers–implicated in the regulation of appetite in …

Enhancement of intragastric acid stability of a fat emulsion meal delays gastric emptying and increases cholecystokinin release and gallbladder contraction

L Marciani, M Wickham, G Singh… - American Journal …, 2007 - journals.physiology.org
Preprocessed fatty foods often contain calories added as a fat emulsion stabilized by
emulsifiers. Emulsion stability in the acidic gastric environment can readily be manipulated …

Effect of intragastric acid stability of fat emulsions on gastric emptying, plasma lipid profile and postprandial satiety

L Marciani, R Faulks, MSJ Wickham, D Bush… - British Journal of …, 2008 - cambridge.org
Fat is often included in common foods as an emulsion of dispersed oil droplets to enhance
the organoleptic quality and stability. The intragastric acid stability of emulsified fat may …

Diet, food intake, and disturbed physiology in the pathogenesis of symptoms in functional dyspepsia

C Feinle-Bisset, R Vozzo, M Horowitz… - Official journal of the …, 2004 - journals.lww.com
Diet, Food Intake, and Disturbed Physiology in the Pathogene... : Official journal of the American
College of Gastroenterology | ACG Diet, Food Intake, and Disturbed Physiology in the …

Low dose lipid formulations: effects on gastric emptying and biliary secretion

GA Kossena, WN Charman, CG Wilson… - Pharmaceutical …, 2007 - Springer
Purpose Food stimulates changes to gastrointestinal secretion and motility patterns,
however, the effect of smaller quantities of lipid, such as that contained in a lipid-based drug …

High-fat diet effects on gut motility, hormone, and appetite responses to duodenal lipid in healthy men

KA Boyd, DG O'Donovan, S Doran… - American Journal …, 2003 - journals.physiology.org
There is evidence that gastrointestinal function adapts in response to a high-fat (HF) diet.
This study investigated the hypothesis that an HF diet modifies the acute effects of duodenal …

The effect of posture on gastric emptying and intragastric distribution of oil and aqueous meal components and appetite

M Horowitz, K Jones, MAL Edelbroek, AJPM Smout… - Gastroenterology, 1993 - Elsevier
Background: It is uncertain whether gastric emptying of fat is determined mainly by its
physical characteristics or chemical composition. In particular, the intragastric distribution of …