Radiopharmaceutical therapy (RPT) is emerging as a safe and effective targeted approach
to treating many types of cancer. In RPT, radiation is systemically or locally delivered using …

Human serum albumin (HSA), the most abundant protein in plasma, is a monomeric multi-
domain macromolecule, representing the main determinant of plasma oncotic pressure and …

The antigen-binding capacity of the paired variable domains of an antibody is well
established. The observation that the isolated heavy chains of anti-hapten antibodies retain …

NRYBAZVQPHGZNS-ZSOCWYAHSA-N leptin Chemical compound O= C ([C@ H](CO) NC
(= O)[C@ H](CC (C) C) NC (= O)[C@ H](CC (O)= O) NC (= O)[C@ H](CC (C) C) NC …

Antibody technologies are being increasingly applied in the field of toxinology. Fuelled by
the many advances in immunology, synthetic biology, and antibody research, different …

▪ Abstract Antibodies are unique in their high affinity and specificity for a binding partner, a
quality that has made them one of the most useful molecules for biotechnology and …

Aptamers are small oligonucleotides that are selected to bind tightly and specifically to a
target molecule. We sought to determine whether aptamers have potential for in vivo …

Whereas over 85% of human cancers are solid tumors, of the 8 monoclonal antibodies
(mAbs) currently approved for cancer therapy, 25% are directed at solid tumor surface …

Noninvasive molecular imaging approaches include nuclear, optical, magnetic resonance
imaging, computed tomography, ultrasound, and photoacoustic imaging, which require …

We recently demonstrated that a human recombinant scFv, L19, reacting with the ED‐B
domain of fibronectin, a marker of angiogenesis, selectively targets tumoral vasculature in …