Tenascin-C is an extracellular matrix glycoprotein that is specifically and transiently
expressed upon tissue injury. Upon tissue damage, tenascin-C plays a multitude of different …

Matrix metalloproteinases (MMPs), also known as matrixins, belong to a group of zinc-
dependent proteins, which are thought to play a central role in the breakdown of …

Matrix metalloproteinases (MMPs) are members of the neutral proteinase family. They were
previously thought to be anti-fibrotic because of their ability to degrade and remodel of …

Object Arteriovenous malformations (AVMs) are classically described as congenital static
lesions. However, in addition to rupturing, AVMs can undergo growth, remodeling, and …

The matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases belonging to the
metzincin superfamily. There are at least 23 members of MMPs ever reported in human, and …

High expression of the extracellular matrix component tenascin-C in the tumor
microenvironment correlates with decreased patient survival. Tenascin-C promotes cancer …

Abstract Cerebral Cavernous Malformation (CCM) is a vascular disease of proven genetic
origin, which may arise sporadically or is inherited as an autosomal dominant condition with …

Venous malformations (VMs) can cause significant morbidity, particularly because they
enlarge over time and become symptomatic. The purpose of this study was to determine the …

Angiogenesis plays a significant role in the human body, from wound healing to tumor
progression.“Angiogenic switch” indicates a time‐restricted event where the imbalance …

The extent of tumor removal determines the effectiveness of postoperative oncotherapy. This
is especially true for primary brain tumors, where peritumoral invasion usually makes radical …