Pathogenic Mycobacterium tuberculosis complex organisms (MTBC) primarily cause
pulmonary tuberculosis (PTB); however, MTBC are also capable of causing disease in …

Objectives To estimate the pooled proportion of extensively drug-resistant tuberculosis (XDR-
TB) and pre-extensively drug-resistant tuberculosis (pre-XDR-TB) in patients with multidrug …

Background Drug-resistant tuberculosis and extrapulmonary tuberculosis are the world
major public health issues. Although some primary studies have been reported on the …

Pyrazinamide (PZA) is an essential first-line tuberculosis drug for its unique mechanism of
action active against multidrug-resistant-TB (MDR-TB). Thus, the aim of updated meta …

Purpose This study examined the patterns and frequency of genetic changes responsible for
resistance to first-line (rifampicin and isoniazid), fluoroquinolones, and second-line …

Background The genetic diversity of Mycobacterium tuberculosis complex (MTBC) strains
was characterized among isolates from individuals with pulmonary tuberculosis (PTB) …

Tuberculosis (TB) is a major public health concern that results in significant morbidity and
mortality, particularly in middle-to low-income countries. Extra-pulmonary tuberculosis …

Background Drug-resistant tuberculosis (DR-TB) is a threat to tuberculosis (TB) control.
Extra-pulmonary forms of DR-TB (DR-epTB) are not well characterized. This review …

Objectives There are few reports on extrapulmonary tuberculosis/human immunodeficiency
virus (EPTB/HIV) co-infection patients, especially the resistance profile of culture-confirmed …

Introduction The population structure of Mycobacterium tuberculosis complex (MTBC) in
Ethiopia is diverse but dominated by Euro-American (Lineage 4) and East-African-Indian …