Proteases regulate important pathophysiological processes in human body such as
homeostasis, blood coagulation, fibrinolysis, tumor progression, etc. These biological effects …

Accumulation of fibrin in blood vessels significantly increases thrombosis, leading to
myocardial infraction and other cardiovascular diseases. Microbial enzymes are one option …

Streptokinase is an extracellular protein, extracted from certain strains of beta hemolytic
streptococcus. It is a non-protease plasminogen activator that activates plasminogen to …

Materials and Methods The rate of streptokinase production evaluated under the effect of
changes on some fermentation factors. Moreover, due to the specific structure of …

Objectives: To produce an effective recombinant streptokinase (rSK) from pathogenic
Streptococcus pyogenes isolate in yeast, and evaluate its potential for thrombolytic therapy …

Background Streptokinase is a potent activator of plasminogen to plasmin, the enzyme that
can solubilize the fibrin network in blood clots. Streptokinase is currently used in clinical …

Introduction: Thrombosis and the blockage of blood vessels with clots, can lead to acute
myocardial infarction and some times even death. Aside from surgical interventions to …

Background: Streptokinase, the most well-known fibrinolytic drug, has long been used in the
treatment of myocardial infarction. This enzyme is produced from beta-hemolytic bacteria. In …

ﯽﻣ ﺪﯿﻟﻮﺗ سﻮﮐﻮﮐﻮﺘﭘﺮﺘﺳا جرﺎـﺧ ﻦﯿﺌﺗوﺮـﭘ ﮏﯾ ﻢﯾﺰﻧآ ﻦﯾا. دﻮﺷ ﻞﯾﺪـﺒﺗ ﺐﺒـﺳ و هدﻮـﺑ يزﺎـﺌﺗوﺮﭘ ﺖﯿﺻﺎﺧ ﺪﻗﺎﻓ ﻪﮐ ﺖﺳا ﯽﻟﻮﻠﺳ ﯽﻣ لﺎﻌﻓ
ﻦﯿﻤﺳﻼﭘ ﻪﺑ نژﻮﻨﯿﻤﺳﻼﭘ ﯽـﻣ ﻪـﮐ دﻮﺷ ﻦﯾﺮـﺒﯿﻓ ﺪـﻧاﻮﺗ ﺪـﯾرو زﻮـﺒﻣوﺮﺗ نﺎـﻣرد رد زﺎﻨﯿﮐﻮﺘﭘﺮﺘـﺳا. ﺪـﻨﮐ ﻪـﯾﺰﺠﺗ ار ﻪﺘﺨﻟ ﺮﺑرﺎﮐ ﻪﯾر …‎