Chemical characterization of tobacco-free “modern” oral nicotine pouches and their position on the toxicant and risk continuums

D Azzopardi, C Liu, J Murphy - Drug and chemical toxicology, 2022 - Taylor & Francis
As compared with cigarette smoking, use of Swedish snus is associated with significantly
fewer health risks. Nicotine pouches (NPs), a new form of oral nicotine product, are …

Classification, perception, and toxicity of emerging flavored oral nicotine pouches

SB Shaikh, C Newton, WC Tung, Y Sun, D Li… - International Journal of …, 2023 - mdpi.com
Introduction: Oral Nicotine Pouches (ONPs) are the new form of nicotine pouches that have
become a type of emerging smokeless tobacco product sold by various tobacco companies …

A randomised study to assess the nicotine pharmacokinetics of an oral nicotine pouch and two nicotine replacement therapy products

D Azzopardi, J Ebajemito, M McEwan, OM Camacho… - Scientific reports, 2022 - nature.com
Nicotine replacement therapies (NRTs) are intended for short-term use to help cigarette
smokers to quit. Some smokers find NRTs ineffective or seek a more satisfactory source of …

Nicotine pouch product awareness, interest and ever use among US adults who smoke, 2021

M Hrywna, NJ Gonsalves, CD Delnevo… - Tobacco …, 2023 - tobaccocontrol.bmj.com
Background Tobacco-free nicotine pouches are one of the fastest growing tobacco product
categories in the US market. However, data on awareness, appeal or ever use of these …

A randomised study to investigate the nicotine pharmacokinetics of oral nicotine pouches and a combustible cigarette

M McEwan, D Azzopardi, N Gale, OM Camacho… - European journal of …, 2022 - Springer
Abstract Background and Objectives Nicotine pouches (NPs) are a relatively new type of
oral smokeless tobacco-free nicotine product. Currently, few data are available on the …

Flavor classification/categorization and differential toxicity of oral nicotine pouches (ONPs) in oral gingival epithelial cells and bronchial epithelial cells

SB Shaikh, WC Tung, C Pang, J Lucas, D Li, I Rahman - Toxics, 2022 - mdpi.com
Oral nicotine pouches (ONPs) are a modern form of smokeless tobacco products sold by
several brands in the US, which comprise a significant portion of non-combustible nicotine …

Nicotine pouches: a review for the dental team

J M. Jackson, A Weke, R Holliday - British Dental Journal, 2023 - nature.com
Nicotine pouches are tobacco-free products that are becoming increasingly popular in the
UK. They are held between the user's lip and gum to provide a source of nicotine. This …

A randomised, open-label, cross-over clinical study to evaluate the pharmacokinetic, pharmacodynamic and safety and tolerability profiles of tobacco-free oral nicotine …

F Chapman, S McDermott, K Rudd, V Taverner… - …, 2022 - Springer
Rationale Tobacco harm reduction (THR) involves encouraging adult smokers who would
otherwise continue to smoke to transition to less harmful forms of nicotine delivery. These …

Oral nicotine pouches with an aftertaste? Part 2: in vitro toxicity in human gingival fibroblasts

S Rinaldi, E Pieper, T Schulz, R Zimmermann… - Archives of …, 2023 - Springer
Nicotine pouches contain fewer characteristic toxicants than conventional tobacco products.
However, the associated risks in terms of toxicity and addiction potential are still unclear …

Market survey of modern oral nicotine products: determination of select HPHCs and comparison to traditional smokeless tobacco products

JJ Jablonski, AG Cheetham, AM Martin - Separations, 2022 - mdpi.com
In an effort to combat the risks associated with traditional tobacco products, tobacco product
innovation has been redirected towards reducing the consumer's potential exposure to …