A critical review of LET-based intensity-modulated proton therapy plan evaluation and optimization for head and neck cancer management

W Deng, Y Yang, C Liu, M Bues… - … Journal of Particle …, 2021 - meridian.allenpress.com
In this review article, we review the 3 important aspects of linear-energy-transfer (LET) in
intensity-modulated proton therapy (IMPT) for head and neck (H&N) cancer management …

State-of-the-art and potential of experimental microdosimetry in ion-beam therapy

G Magrin, H Palmans, M Stock, D Georg - Radiotherapy and Oncology, 2023 - Elsevier
In radiotherapy, radiation-quality should be an expression of the biological and physical
characteristics of ionizing radiation such as spatial distribution of ionization or energy …

Integrating an open source Monte Carlo code “MCsquare” for clinical use in intensity‐modulated proton therapy

W Deng, JE Younkin, K Souris, S Huang… - Medical …, 2020 - Wiley Online Library
Purpose To commission an open source Monte Carlo (MC) dose engine,“MCsquare” for a
synchrotron‐based proton machine, integrate it into our in‐house C++‐based I/O user …

Monte Carlo methods for device simulations in radiation therapy

H Park, H Paganetti, J Schuemann… - Physics in Medicine & …, 2021 - iopscience.iop.org
Monte Carlo (MC) simulations play an important role in radiotherapy, especially as a method
to evaluate physical properties that are either impossible or difficult to measure. For …

Treatment planning for proton therapy: what is needed in the next 10 years?

H Nystrom, MF Jensen… - The British Journal of …, 2020 - academic.oup.com
Treatment planning is the process where the prescription of the radiation oncologist is
translated into a deliverable treatment. With the complexity of contemporary radiotherapy …

Prompt gamma spectroscopy retrieval algorithm for element and density measurements accelerated by cloud computing

JL Wang, XG Wu, ZF Li, SQ Xie, DQ Hei, ZH Zhao… - Frontiers in …, 2022 - frontiersin.org
Prompt gamma ray in proton therapy is the product of a nuclear reaction between a proton
and a target. The characteristic energies and intensities of prompt gamma lines can be used …

[HTML][HTML] Heavy concrete shielding properties for carbon therapy

JL Wang, JJ Lu, DJ Ding, WH Jiang, YD Li… - Nuclear Engineering …, 2023 - Elsevier
As medical facilities are usually built at urban areas, special concrete aggregates and
evaluation methods are needed to optimize the design of concrete walls by balancing …

Range verification of a clinical proton beam in an abdominal phantom by co-registration of ionoacoustics and ultrasound

J Schauer, HP Wieser, J Lascaud… - Physics in Medicine …, 2023 - iopscience.iop.org
Objective. The range uncertainty in proton radiotherapy is a limiting factor to achieve
optimum dose conformity to the tumour volume. Ionoacoustics is a promising approach for in …

First benchmarking of the BIANCA model for cell survival prediction in a clinical hadron therapy scenario

MP Carante, G Aricò, A Ferrari… - Physics in Medicine …, 2019 - iopscience.iop.org
In the framework of RBE modelling for hadron therapy, the BIANCA biophysical model was
extended to O-ions and was used to construct a radiobiological database describing the …

Benchmarking a GATE/Geant4 Monte Carlo model for proton beams in magnetic fields

F Padilla‐Cabal, J Alejandro Fragoso… - Medical …, 2020 - Wiley Online Library
Purpose Magnetic resonance guidance in proton therapy (MRPT) is expected to improve its
current performance. The combination of magnetic fields with clinical proton beam lines …