Immunosuppressive agents are commonly used in the nephrologist's practice in the
treatment of autoimmune and immune-mediated diseases and transplantation, and they are …

Advances in multimodal immunotherapy have significantly reduced acute rejection rates and
substantially improved 1-year graft survival following renal transplantation. However, long …

These guidelines cover the care of patients from the period following kidney transplantation
until the transplant is no longer working or the patient dies. During the early phase …

The long-term management of maintenance immunosuppression in kidney transplant
recipients remains complex. The vast majority of patients are treated with the calcineurin …

Context Antibody-based induction therapy plus calcineurin inhibitors (CNIs) reduce acute
rejection rates in kidney recipients; however, opportunistic infections and toxic CNI effects …

Immunosuppression regimens used in solid organ transplant have evolved significantly over
the past 70 years in the United States. Early immunosuppression and targets for allograft …

Advances in immunosuppression have propelled kidney transplantation from a scientific
curiosity to the optimal treatment for patients with end stage kidney disease. Declining rates …

Background The present review is part of the ESCMID Study Group for Infections in
Compromised Hosts (ESGICH) Consensus Document on the safety of targeted and …

Background Prolonging kidney transplant survival is an important clinical priority. Induction
immunosuppression with antibody therapy is recommended at transplantation and non …

Our understanding of the involvement of the gut microbiota (GM) in human health has
expanded exponentially over the last few decades, particularly in the fields of metabolism …